File:Fluorescence In situ Hybridization (FISH) assay.JPG

From Embryology

Fluorescence_In_situ_Hybridization_(FISH)_assay.JPG(696 × 222 pixels, file size: 11 KB, MIME type: image/jpeg)

This is a FISH (fluorescence in situ hybridization) analysis X chromosomes within a mosaic nucleus of XXY, XXXY, and XXXXY respectively. Each section (out of the three shown)illustrates a single nucleus. Within each nucleus the X chromosomes have been marked with a green fluoresent protein, allowing for their observation. As can be seen, the first nucleus is of standard Klinefelter's karyotype with two X chromosomes, and so on. These cells were isolated from a single patient expressing mosaic Klinefelter's syndrome.


<pubmed>17880714</pubmed>| PMC3105055

Copyright - © 2007 Dueñas-Arias et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


+ Research image is very relevant to group topic. +/- The legend does describe what is shown in the figure, but it is not an accurate description (what is the red fluorescence?) and therefore does not provide a complete element of peer teaching. - No assessment of citation included as reformatted by coordinator. Mark Hill 19:05, 1 October 2011 (EST) I have reformatted the citation. Please follow the methodology as I have advised you in class before. Please add a more complete description of the image above.

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Cite this page: Hill, M.A. (2024, June 17) Embryology Fluorescence In situ Hybridization (FISH) assay.JPG. Retrieved from

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current19:15, 30 September 2011Thumbnail for version as of 19:15, 30 September 2011696 × 222 (11 KB)Z3289066 (talk | contribs)This is a FISH (fluorescence in situ hybridization) analysis X chromosomes within a mosaic nucleus of XXY, XXXY, and XXXXY respectively. The bright green points indicate the presence of an X chromosome. Copyright - © 2007 Dueñas-Arias et al; license

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