File:Aschheim-Zondek Test 1928.gif
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Aschheim-Zondek_Test_1928.gif (449 × 600 pixels, file size: 280 KB, MIME type: image/gif, looped, 10 frames, 11 s)
Aschheim-Zondek Test (1928)
The basis of the original historic Aschheim-Zondek[1] test developed in 1928 was to identify the changes in immature female mouse genital system by female human urine injected subcutaneously into these immature mice.
- If the woman was pregnant - the presence of hormones (hCG) induced changes in the mouse genital tract physiologically similar to those produced by sex hormones.
- follicle maturation, corpora heamorrhagicum and corpora lutea formation.
- If the woman was not pregnant - there were no changes induced.
This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus frog.
Animation based upon original line drawings.[2]
- Links: Pregnancy Test | Menstrual Cycle | Week 2 | Mouse Development | Frog Development
Reference
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current | 12:02, 15 November 2012 | 449 × 600 (280 KB) | Z8600021 (talk | contribs) | added ovary histology | |
12:01, 15 November 2012 | 449 × 600 (278 KB) | Z8600021 (talk | contribs) | added ovary histology | ||
10:55, 15 November 2012 | 449 × 600 (157 KB) | Z8600021 (talk | contribs) |
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