Endocrine - Thymus Development: Difference between revisions
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[[2009_Lecture_11|Lecture - Head Development]] | [http://embryology.med.unsw.edu.au/Notes/endocrine13.htm UNSW Embryology - Thymus Development] | [[2009_Lecture_11|Lecture - Head Development]] | [http://embryology.med.unsw.edu.au/Notes/endocrine13.htm UNSW Embryology - Thymus Development] | ||
The thymus has two origins for the lymphoid thymocytes and the thymic epithelial cells. The thymic epithelium begins as two flask-shape endodermal diverticula that form from the third pharyngeal pouch and extend lateralward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta. | |||
* Thymus - bone-marrow lymphocyte precursors become thymocytes, and subsequently mature into T lymphocytes (T cells) | * Thymus - bone-marrow lymphocyte precursors become thymocytes, and subsequently mature into T lymphocytes (T cells) | ||
Revision as of 13:00, 25 April 2010
Lecture - Head Development | UNSW Embryology - Thymus Development
The thymus has two origins for the lymphoid thymocytes and the thymic epithelial cells. The thymic epithelium begins as two flask-shape endodermal diverticula that form from the third pharyngeal pouch and extend lateralward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta.
- Thymus - bone-marrow lymphocyte precursors become thymocytes, and subsequently mature into T lymphocytes (T cells)
- Thymus hormones - thymosins stimulate the development and differentiation of T lymphocytes
Thymus Development
- Endoderm - third pharyngeal pouch
- Week 6 - diverticulum elongates, hollow then solid, ventral cell proliferation
- Thymic primordia - surrounded by neural crest mesenchyme, epithelia/mesenchyme interaction
