Nephron Development Movie

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Embryology - 26 May 2024    Facebook link Pinterest link Twitter link  Expand to Translate  
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<html5media height="400" width="500">File:Nephron_development.mp4</html5media>

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Renal 001 icon.jpg

Early Renal Development

This animation shows the process of early renal (kidney) development.

Legend

  • Ureteric Bud - developing ureter, pelvis, calyces, collecting ducts
  • Metanephric Blastema (intermediate mesoderm) - developing glomeruli, capsule, nephron tubules


Links: MP4 version | Urogenital Sinus Movie | Renal System Development | Movies

Nephron Development

  • disorganised mesenchymal cells become a highly organised epithelial tubule
  • Condensation - groups of about 100 cells condense tightly together to form a distinct mass
  • Epithelialisation - condensed cells lose their mesenchymal character and gain epithelial
  • At end of this period formed a small epithelial cyst complete with a basement membrane, cell-cell junctions and a defined cellular apico-basal polarity.

Early morphogenesis

  • cyst invaginates twice to form a comma
  • then a S-shaped body one invagination site later becomes the glomerular cleft
  • At about this time blood vessel progenitors invade cleft to begin construction of vascular component of glomerulus
  • Tubule maturation specialised transporting segments of nephron differentiate complex of convoluted tubules is created


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Cite this page: Hill, M.A. (2024, May 26) Embryology Nephron Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Nephron_Development_Movie

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G