ANAT2341 Lab 7: Difference between revisions

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==Organogenesis Lab==


Please note the different location for this week’s practical class: Wallace Wurth Teaching Lab 116.


== 1. QUIZ ==


== 2. Guest Lecturer - Annemiek Beverdam==
'''PRACTICAL CLASS PROGRAM'''
{|
| width=185px| [[File:Annemiek Beverdam.jpg|180px]]


Dr Annemiek Beverdam
* Weekly Quiz + revision (15 minutes)
| valign=top|'''Developmental and Regenerative Dermatology'''
* Practical class activities (90 minutes)
<br><br>
* Practical Class Revision (15 minutes)
Dr. Beverdam studies the genetic processes that govern development, homeostasis and regeneration of the skin in the mouse. Her research aims at understanding the genetic and molecular basis of developmental and human regenerative skin diseases such as skin cancer, which affects 2 out of 3 Australians in their life time.


She recently made the pivotal discovery that Yes-associated protein (YAP) functions as a key molecular switch in epidermal stem/progenitor cell proliferation and differentiation (Beverdam et al., JID 2013). Dr. Beverdam currently investigates the developmental genetic context in which YAP functions to control skin stem/progenitor cells in normal and in disrupted skin biology. She employs genetically manipulated mouse models, human skin samples, advanced imaging technology such as confocal microscopy and whole mouse in vivo imaging, gene and protein expression analyses and whole genome approaches to address her research questions. Her research will open up exciting new avenues for translational research and the development of treatments for human regenerative skin disease.
|}


[[Media:ANAT2341_Skin_Research_Lab_.pdf|Lecture slides]]
'''PRACTICAL CLASS ACTIVITIES (90 minutes)'''
 
* Fertile egg dissections, stage definition, and annotations of structures (first 60 minutes)
* Observation of skeletal preparations of chicken and mouse foetuses (first 60 minutes)
* Group presentation of annotated embryo images (final 30 minutes)
 
 
'''LEARNING OBJECTIVES'''
 
* Understanding early neurulation, mesoderm and heart development, and being able to identify the defining structures in the chicken embryo.
* Understanding craniofacial and limb development and being able to identify the defining structures in chicken embryos.
* Understanding the development of the musculoskeletal system and being able to identify the defining structures in chicken embryos.
* Be able to apply basic practical laboratory skills and work with embryo and regeneration models.
* Be able to work effectively within a small team to complete academic tasks.
* Be able to present embryonic observations effectively and appropriately to an audience
* Be able to self-manage and work independently with an ability to take responsibility for their own learning, and an appreciation of the value of learning.
 
 
 
[[File:Chicken_Embryo_Hamburger_stages.jpg|600px|link=Hamburger Hamilton Stages]]
 
''These are the Hamburger stages of chicken development''
 
 
See also the [https://www.jove.com/video/306/windowing-chicken-eggs-for-developmental-studies JoVE article on chicken egg preparation]: <pubmed>18989413</pubmed>
 
 
===Additional Chicken Links===
[[File:Viktor Hamburger.jpg|thumb|alt=Viktor Hamburger|link=Embryology History - Viktor Hamburger|Viktor Hamburger (1900 – 2001)]]
More about chicken embryogenesis: [[Chicken Development]] | [[Hamburger Hamilton Stages]]
<br>
<br>
{{Chicken links}}
<br>
<br>
<br>
 
{{2018ANAT2341}}
<gallery>
File:HHstage1-4.jpg|stage 1-4
File:HHstage5-10.jpg|stages 5-10
File:HHstage11-14.jpg|stages 11-14
File:HHstage15-18.jpg|stages 15-18
File:HHstage19-21.jpg|stages 19-21
File:HHstage22-25.jpg|stages 22-25
File:HHstage26-28.jpg|stages 26-28
File:HHstage29-32.jpg|stage 29-32
</gallery>
 
[[File:Mouse_vs_Human_embryogenesis.jpg]]
 
''This figure compares the human and mouse developmental stages''
 
More about Mouse embryogenesis: [[Mouse Timeline Detailed]]
 
 
{{Chicken}}
 
===External Links===
{{External Links}}
 
* JOVE - [http://www.jove.com/science-education/5153/an-introduction-to-the-chick-gallus-gallus-domesticus An Introduction to the Chicken]

Latest revision as of 10:38, 22 October 2019

Organogenesis Lab

Please note the different location for this week’s practical class: Wallace Wurth Teaching Lab 116.


PRACTICAL CLASS PROGRAM

  • Weekly Quiz + revision (15 minutes)
  • Practical class activities (90 minutes)
  • Practical Class Revision (15 minutes)


PRACTICAL CLASS ACTIVITIES (90 minutes)

  • Fertile egg dissections, stage definition, and annotations of structures (first 60 minutes)
  • Observation of skeletal preparations of chicken and mouse foetuses (first 60 minutes)
  • Group presentation of annotated embryo images (final 30 minutes)


LEARNING OBJECTIVES

  • Understanding early neurulation, mesoderm and heart development, and being able to identify the defining structures in the chicken embryo.
  • Understanding craniofacial and limb development and being able to identify the defining structures in chicken embryos.
  • Understanding the development of the musculoskeletal system and being able to identify the defining structures in chicken embryos.
  • Be able to apply basic practical laboratory skills and work with embryo and regeneration models.
  • Be able to work effectively within a small team to complete academic tasks.
  • Be able to present embryonic observations effectively and appropriately to an audience
  • Be able to self-manage and work independently with an ability to take responsibility for their own learning, and an appreciation of the value of learning.


Chicken Embryo Hamburger stages.jpg

These are the Hamburger stages of chicken development


See also the JoVE article on chicken egg preparation: <pubmed>18989413</pubmed>


Additional Chicken Links

Viktor Hamburger
Viktor Hamburger (1900 – 2001)

More about chicken embryogenesis: Chicken Development | Hamburger Hamilton Stages

Chicken Links: Introduction | Chicken stages | Hamburger Hamilton Stages | Witschi Stages | Placodes | Category:Chicken
Historic Chicken Embryology  
1883 History of the Chick | 1900 Chicken Embryo Development Plates | 1904 X-Ray Effects | 1910 Somites | 1914 Primordial Germ Cells

1919 Lillie Textbook | 1920 Chick Early Embryology | 1933 Neural | 1939 Sternum | 1948 Limb | Movie 1961 | Historic Papers


Mouse vs Human embryogenesis.jpg

This figure compares the human and mouse developmental stages

More about Mouse embryogenesis: Mouse Timeline Detailed


chicken

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.