2011 Lab 8: Difference between revisions
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==Urogenital Development== | |||
This practical will introduce the topic of urogenital differentiation during development through a series of online resource pages. | |||
'''Aim:''' This practical is an introduction to the earliest events in Sexual Differentiation. | |||
'''Key Concepts:''' Intermediate mesoderm, primordial germ cells, renal development, bladder development, gonad, internal genitalia, external genitalia, ovary, testes, puberty, hormonal changes, gametogenesis, abnormalities. | |||
==Background== | |||
{| | |||
| [[File:Historic-testis.jpg|140px]] | |||
[[File:Historic-ovary.jpg|200px]] | |||
'''Historic Gonad Images''' | |||
| valign="top" | Two key systems, neural and reproductive, develop over an extended period from the early embryo to puberty and the emerging adult. The genital system is closely linked developmentally to the urinary system, often called the urogenital system. This practical will therefore cover early development of both system. | |||
In understanding embryonic sexual development, think of a cascade of sequence dependent events that transform indifferent gonads, internal and external genitalia into distinct male and female structures. | |||
The process begins with gonad differentiation, which itself is tied developmentally back at the initial event of fertilization and the presence of either a Y or X chromosome in the sperm. | |||
The endpoint of development could be considered the post-puberty active reproductive system. Interestingly, recent research is pointing to a link between neural and reproductive systems in how male and female brains may differentially develop under the influence of sex hormones and perhaps even the sex chromosomes. | |||
* There are 6 pages to work through in today's practical class, listed beside the small BGD icon at the top and bottom of each page. | |||
* Additional information sections are not part of the practical class content. | |||
|} | |||
==Genital Timeline== | |||
24 days - intermediate mesoderm, pronephros primordium | |||
28 days - mesonephros and mesonephric duct | |||
35 days - uteric bud, metanephros, urogenital ridge | |||
42 days - cloacal divison, gonadal primordium (indifferent) | |||
49 days - paramesonephric duct, gonadal differentiation | |||
56 days - paramesonephric duct fusion (female) | |||
100 days - primary follicles (ovary) | |||
==Textbooks== | |||
{| | |||
| [[File:The Developing Human, 8th edn.jpg|80px]] | |||
| Moore, K.L. & Persuad, T.V.N. (2008). <i>The Developing Human: clinically oriented embryology</i> (8<sup>th</sup> ed.). Philadelphia: Saunders. | |||
The following chapter links only work with a UNSW connection and can also be accessed through this [http://searchfirst.library.unsw.edu.au/primo_library/libweb/action/search.do?vid=UNSW&fn=search&vl(freeText0)=UNSW_SFX14190000000048007 UNSW Library connection]. | |||
* [http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-1-4160-3706-4&eid=4-u1.0-B978-1-4160-3706-4..50015-3 Chapter 12 - The Urogenital System] | |||
|- | |||
| [[File:Larsen's human embryology 4th edn.jpg|80px]] | |||
| Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R. and Francis-West, P.H. (2009). <i>Larsen’s Human Embryology</i> (4<sup>th</sup> ed.). New York; Edinburgh: Churchill Livingstone. | |||
The following chapter links only work with a UNSW connection and can also be accessed through this [http://searchfirst.library.unsw.edu.au/primo_library/libweb/action/search.do?vid=UNSW&fn=search&vl(freeText0)=UNSW_SFX14190000000047996 UNSW Library connection]. | |||
* [http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-0-443-06811-9&eid=4-u1.0-B978-0-443-06811-9..10015-6 Chapter 15 - Development of the Urogenital System] | |||
|- | |||
| [[File:Logo.png|80px]] | |||
| Hill, M.A. (2011) <i>UNSW Embryology</i> (11<sup>th</sup> ed.). Sydney:UNSW. | |||
* [[BGD_Lecture_-_Sexual_Differentiation|BGDB Lecture 2011]] | |||
* [[Media:BGDB PracManual 2011 Practical 11.pdf|BGDB Practical Manual 2011 Practical 11]] | |||
* {{Template:Genital Links}} | |||
|} |
Revision as of 16:04, 21 September 2011
2011 Lab 8: Introduction | Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | Quiz | Online Assessment |
Urogenital Development
This practical will introduce the topic of urogenital differentiation during development through a series of online resource pages.
Aim: This practical is an introduction to the earliest events in Sexual Differentiation.
Key Concepts: Intermediate mesoderm, primordial germ cells, renal development, bladder development, gonad, internal genitalia, external genitalia, ovary, testes, puberty, hormonal changes, gametogenesis, abnormalities.
Background
Genital Timeline
24 days - intermediate mesoderm, pronephros primordium
28 days - mesonephros and mesonephric duct
35 days - uteric bud, metanephros, urogenital ridge
42 days - cloacal divison, gonadal primordium (indifferent)
49 days - paramesonephric duct, gonadal differentiation
56 days - paramesonephric duct fusion (female)
100 days - primary follicles (ovary)