2011 Group Project 2: Difference between revisions

Revision as of 22:32, 10 August 2011

Note - This page is an undergraduate science embryology student group project 2011.

Duchennes Muscular dystrophy

--z3288827 21:53, 8 August 2011 (EST)

Review Article

Hey guys, just found a review article that I thought was rather interesting, it's an animal model for Duchenne's muscular dystrophy[1]. I also found a primary journal article that discusses drug delivery for the condition [2]. I will print these articles for myself tonight and give them a quick read tomorrow and then paste a quick summary of the articles here just for you guys to consider :)

References

[1] Nakamura A., Takeda S.; Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications, J. Biomedicine and Biotechnology Vol. 2011, Article ID 184393

[2] Yukihara et al; Effective Drug Delivery System for Duchenne Muscular Dystrophy Using Hybrid Liposomes Including Gentamicin along with Reduced Toxicity, J. Biol. Pharm. Bull, Volume 34, No. 5 pp. 712-716

More Articles

Hello! Those articles above look great. From the little research I have done it looks like there is plenty of research to choose from, so that makes our job a little easier I hope. The primary journal article I found talks about the expression of the DMD Gene Products in Embryonic Stem Cells, so hoping that this will allow us to elaborate a bit on the genetic aspects of the development and potential early identification, as symptoms do not usually appear in humans until a few years of age [3]. Also the review article I found refers to two other types of muscular dystrophies as well as DMD (SCARMD, CMD), highlighting many key developments in research. Seem to be very informative, also refers a bit to the importance of animal models in these developments [4].

--z3288196 22:32, 10 August 2011 (EST)

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 == More Articles ==
-Hello! Those articles above look great. From the little research I have done it looks like there is plenty of research to choose from, so that makes our job a little easier I hope. The primary journal article I found talks about the expression of the DMD Gene Products in Embryonic Stem Cells, so hoping that this will allow us to elaborate a bit on the genetic aspects of the development and potential early identification, as symptoms do not usually appear until a few years of age [http://www.jbc.org/content/267/30/21289.full.pdf+html]. Also the review article I found refers to two other types of muscular dystrophies as well as DMD (SCARMD, CMD),  highlighting many key developments in research. Seem to be very informative, also refers a bit to the importance of animal models in these developments, so the article posted above seems to be quite important to our understanding of these human muscular dystrophies[http://www.physiology.uiowa.edu/campbell/Publications/PDF/157Campbell.pdf].
+Hello! Those articles above look great. From the little research I have done it looks like there is plenty of research to choose from, so that makes our job a little easier I hope. The primary journal article I found talks about the expression of the DMD Gene Products in Embryonic Stem Cells, so hoping that this will allow us to elaborate a bit on the genetic aspects of the development and potential early identification, as symptoms do not usually appear in humans until a few years of age [http://www.jbc.org/content/267/30/21289.full.pdf+html]. Also the review article I found refers to two other types of muscular dystrophies as well as DMD (SCARMD, CMD),  highlighting many key developments in research. Seem to be very informative, also refers a bit to the importance of animal models in these developments [http://www.physiology.uiowa.edu/campbell/Publications/PDF/157Campbell.pdf].
+--z3288196 22:32, 10 August 2011 (EST)
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