2011 Group Project 1: Difference between revisions
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== Turner | == Turner Syndrome == | ||
Revision as of 11:16, 25 August 2011
Note - This page is an undergraduate science embryology student group project 2011. |
Turner Syndrome
Introduction
- a syndrome derived from the word thalassa (sea) and haima (blood)
- a group of hereditary blood disorders
- reduced or absent beta globin chain synthesis caused by mutations, resulting in reduced Hb in red blood cells (RBC), decreased RBC production and anemia.
- Most thalassemias are inherited as recessive traits.
History
Epidemiology
- Prevalent in Mediterranean countries, the Middle East, Central Asia, India, Southern China, and the Far East as well as countries along the north coast of Africa and in South America.
- Reason for high prevalence across the globe is due to migration and intermarriage between different ethnic groups.
- Approximately 80 to 90 million people are carriers of beta-thalassemia and most are from developed nations, with about 60,000 symptomatic individuals born annually.
- The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world.
- Research shows that about 200,000 patients with thalassemia major have successful outcome in treatment.
Etiology
Clinical manifestations
Diagnostic Procedures
Treatment
Current/future research possibilities
Glossary
References
2011 Projects: Turner Syndrome | DiGeorge Syndrome | Klinefelter's Syndrome | Huntington's Disease | Fragile X Syndrome | Tetralogy of Fallot | Angelman Syndrome | Friedreich's Ataxia | Williams-Beuren Syndrome | Duchenne Muscular Dystrolphy | Cleft Palate and Lip