2011 Group Project 1: Difference between revisions

Revision as of 11:16, 25 August 2011

Note - This page is an undergraduate science embryology student group project 2011.

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 == Introduction ==
-- a syndrome derived from the word thalassa (sea) and haima (blood)
-- a group of hereditary blood disorders
-- reduced or absent beta globin chain synthesis caused by mutations, resulting in reduced Hb in red blood cells (RBC), decreased RBC production and anemia.
-- Most thalassemias are inherited as recessive traits.
 == History ==
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 == Epidemiology ==
-- Prevalent in Mediterranean countries, the Middle East, Central Asia, India, Southern China, and the Far East as well as countries along the north coast of Africa and in South America.
-- Reason for high prevalence across the globe is due to migration and intermarriage between different ethnic groups.
-- Approximately 80 to 90 million people are carriers of beta-thalassemia and most are from developed nations, with about 60,000 symptomatic individuals born annually.
-- The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world.
-- Research shows that about 200,000 patients with thalassemia major have successful outcome in treatment.
 == Etiology ==