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- 11:17, 16 August 2011 Z3389806 talk contribs uploaded File:Melatonin levels in HD patients and controls.jpg (Mean 24 h melatonin levels in HD patients and matched controls. The diurnal melatonin rise was significantly delayed in HD patients by about 01:30 h (p = 0.048). The black bar on the abscissa indicates the dark period (23:00–7:30 h) <ref><pubmed>278062)