Talk:Foundations - Histology Cells and Tissues

Expert Tutorial - Histology

Note only Cells and Tissues has been done not Skin prac yet.

A3

How is the study of animal histology relevant/useful to the study of human histology? Can it be misleading?
- Many of the tissues in animal models closely represents that seen in human tissue.
- Virtual Microscope images are a mix of human and animal tissues. Often human tissue is not available or difficult to prepare.
- By misleading do you mean different from the human tissue? In most cases not that different. In the practicals it is often explained why human tissue was not available/suitable.
How can enzymatic activity, or chemical reactions be studied in histology?
- Some histological methods (immunohistochemistry) do use the presence of active enzymes on antibodies to produce a coloured precipitate in the tissue where the antibody is binding.
- Actual tissue enzyme activity is limited by the type of fixation used in preparing the tissue, and usually only seen in fresh tissues.
Is the study of histology only limited to a structure/function type analysis?
- Histology is the "anatomical study of the microscopic structure of tissues" it extends what you are doing in gross anatomy to the tissue/cell level.

A2

How do you identify the different types of leukocyte by their shape? 
Could you please explain about the features in this virtual slide that was in Science Practical (Introduction to histology - Cells and tissues)

B2

how to differentiate original tissue from the histological slide. i.e. is the slide from a lung/ovary/skin/tracha etcetc
will we have to know how to recognise and differentiate between the different types of tissues from different parts of the body (and if so, how)?

A1

A4

A5

B1

why do we form scar tissue?
why doesn't the body just clear out the dead leucocytes and undergo mitosis to replace the damaged cells (aka not forming a scar?)
is there a benefit that the body makes it into a scar instead of regular tissue?

C

C4

Please explain tight junctions and gap junctions and any other junctions we need to know
Epithelium vs. endothelium vs. mesothelium
How do lymphnodes filter?

C5

What is the difference between the function of granular neutrophils and non--granular monocytes in phagocytosis?
Does plasma as a ground substance have the same compondents as ground substance in other types of connective tissue?
What is matrix, what is it composed of, and what is its function? What is the difference between intracellular and extracellular matrix?

D2

Is the formation of adipose tissue controlled by genetics, and if so how do other factors, such as lifestyle, affect the amount of adipose tissue one has?
Why is there different shaped cells and layer structures in epithelial tissue eg/squamous, stratified etc? Is there a functional difference between shapes and layer organisations?
How do red blood cells operate without a nucleus and organelle? Do they produce their own haemoglobin or is there a set amount when they are produced in the bone marrow?
How does myelin act to speed up the transmission of signals, and why do some nerve fibers not have this myelin sheath?

D3

How do we identify pseudostratified cells?
What exactly is collagen and how can we identify it in slides?
How do we tell the difference between glands and ducts?
Why do different blood cells have different shaped nuclei?
How many different types of tissue fall underneath the term collagen and what are these?

D5

What other stains are there? What are the characteristics of each one?
Clarification of staining process for gram positive and negative.
How does crystal violet and iodine enter the peptidoglycan in gram positive if they can't escape?
What is the difference between the function of granular neutrophil and non-granular monocytes?