2011 Lab 10 - Fetal

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Hearing

  • Week 9 - Mesenchyme surrounding membranous labryinth (otic capsule) chondrifies. (More? Human 10 Week Fetus)
  • Week 12-16 - Capsule adjacent to membranous labryinth undegoes vacuolization to form a cavity (perilymphatic space) around membranous labrynth and fills with perilymph.
  • Week 16-24 - Centres of ossification appear in remaining cartilage of otic capsule form petrous portion of temporal bone. Continues to ossify to form mastoid process of temporal bone.
  • 3rd Trimester - Vibration acoustically of maternal abdominal wall induces startle response in fetus.

Central Pathway

Auditory neural pathway
  • 26 weeks - human brainstem auditory pathway is anatomically formed.
  • 28 weeks - Automated Auditory Brainstem Response ( AABR) can be recorded.

less than 34 weeks - latencies of AABR components (I, III, and V) decrease as a function of gestation