File:Thymus Hassall's corpuscle.jpg
Thymus_Hassall's_corpuscle.jpg (800 × 451 pixels, file size: 84 KB, MIME type: image/jpeg)
Human Thymus Hassall's corpuscle
Human TSLP activates thymic CD11c-positive dendritic cells.
a, TSLP immunostaining showing that Hassall's corpuscles in the thymic medulla express TSLP (red) (left panel). Double staining of TSLP and DC-LAMP showing an association between TSLP-positive Hassall's corpuscles (red) and DC-LAMP-positive activated dendritic cells (blue) (middle panel). Double staining of DC-LAMP and CD11c showing two dendritic cell populations: CD11c+DC-LAMP+ activated dendritic cells (dark brown) and CD11c+DC-LAMP- resting dendritic cells (blue) (right panel).
All scale bars, 50 µm.
b, c, Peripheral blood and thymic dendritic cells stimulated with TSLP or poly(I:C), or cultured in medium only. CD80, CD86 and HLA-DR expression as determined by flow cytometry (b). The numbers in the histograms indicate the mean fluorescence intensity. Production of TARC, MDC, IL-12p70 (the heterodimeric biologically active form of IL-12) and TNF-α by dendritic cells as determined by an enzyme-linked immunosorbent assay (c).
Original file name: Figure 1 Nature03886-f1.jpg
Reference
<pubmed>16121185</pubmed>| Nature
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Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan
| Gwalagizhi | Nyangagi | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:09, 21 February 2011 | | 800 × 451 (84 KB) | S8600021 (talk | contribs) | ==Human Thymus Hassall's corpuscle== Human TSLP activates thymic CD11c-positive dendritic cells. a, TSLP immunostaining showing that Hassall's corpuscles in the thymic medulla express TSLP (red) (left panel). Double staining of TSLP and DC-LAMP showing |
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