File:Hippocampal Formation.jpg
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Figure 1: Hippocampal formation.[1]
Images of the hippocampal formation at the level of the lateral geniculate body from (A) patient 1 and (C) patient 3 show abnormal expansion of CA1 by increased numbers of pyramidal neurons. These are compared with the more usual hippocampal microarchitecture that shows a thinner linear band of neurons in CA1, as seen in (B) a 62-year-old male control. Haematoxylin and eosin, original magnification ×10; scale bar = 1 mm. Arrow indicates bulge/expansion composed of increased numbers of pyramidal cells in (A) patient 1 and (C) patient 3.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References:
- ↑ C.M. Greco, C.S. Navarro, M.R. Hunsaker, I. Maezawa, J.F. Shuler, F. Tassone, M. Delany, J.W. Au, R.F Berman, L. Jin, C. Schumann, P.J. Hagerman and R.J. Hagerman Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol ecular Autism: 2011, 2(1):2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045897/pdf/2040-2392-2-2.pdf
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