Talk:Cell Division - Mitosis
Bipolar metaphase spindle formation in a fucoid alga cell. Normal spindle formation is disrupted by treatment with the Kinesin-5 inhibitor monastrol. Treated zygotes arrest at the spindle assembly check point and produce monasters, multipolar spindles, and numerous cytasters. Spindle microtubules are shown in green and condensed chromatin is shown in red. This month features a guest image which was recently published in BMC Plant Biology.
http://www.biomedcentral.com/bmccellbiol/imageofthemonth/archive/2006/10
Deciphering protein function during mitosis in PtK cells using RNAi
Knockdown of the kinesin Eg5 leads to mitotic defects. Knockdown of Eg5 levels by treatment with siRNA results in cells with monopolar spindles and a mitotic delay (right hand cell). Microtubule staining is shown in green, Eg5 in red and DNA in blue.
