Template:Male Infertility Genes table 1
From Embryology
Gene abbreviation | Name | Gene Location | Online Mendelian Inheritance in Man (OMIM) |
HUGO Gene Nomenclature Committee (HGNC) |
GeneCards (GCID) | Diagnosis |
---|---|---|---|---|---|---|
AURKC | Aurora kinase C | 19q13.43 | 603495 | 11391 | GC19P057230 | Macrozoospermia |
CATSPER1 | Cation channel sperm-associated 1 | 11q13.1 | 606389 | 17116 | GC11M066034 | Asthenozoospermia |
CFTR | Cystic fibrosis transmembrane conductance regulator | 7q31.2 | 602421 | 1884 | GC07P117465 | Obstructive azoospermia |
DNAH1 | Dynein axonemal heavy chain 1 | 3p21.1 | 603332 | 2940 | GC03P052350 | Asthenozoospermia |
DPY19L2 | Dpy-19-like 2 gene | 12q14.2 | 613893 | 19414 | GC12M063558 | Globozoospermia |
GALNTL5 | Polypeptide N-acetylgalactosaminyltransferase-like 5 | 7q36.1 | 615133 | 21725 | GC07P151956 | Asthenozoospermia |
MAGEB4 | MAGE family member B4 | Xp21.2 | 300153 | 6811 | GC0XP030260 | Azoospermia |
NANOS1 | Nanos C2HC-type zinc finger 1 | 10q26.11 | 608226 | 23044 | GC10P119029 | Azoospermia |
NR0B1 | Nuclear receptor subfamily 0 group B member 1 | Xp21.2 | 300473 | 7960 | GC0XM030322 | Azoospermia |
NR5A1 | Nuclear receptor subfamily 5 group A member 1 | 9q33.3 | 184757 | 7983 | GC09M124481 | Azoospermia |
SOHLH1 | Spermatogenesis and oogenesis-specific basic helix–loop–helix 1 | 9q34.3 | 610224 | 27845 | C09M135693 | Azoospermia |
vSPATA16 | Spermatogenesis-associated 16 | 3q26.31 | 609856 | 29935 | GC03M172889 | Globozoospermia |
SYCE1 | Synaptonemal complex central element protein 1 | 10q26.3 | 611486 | 28852 | GC10M133553 | Azoospermia |
TAF4B | TATA-box binding protein-associated factor 4b | 18q11.2 | 601689 | 11538 | GC18P026225 | Azoospermia |
TEX11 | Testis expressed 11 | Xq13.1 | 300311 | 11733 | GC0XM070528 | Azoospermia |
TEX15 | Testis expressed 15, meiosis and synapsis associated | 8p12 | 605795 | 11738 | GC08M030808 | Azoospermia |
WT1 | Wilms tumour 1 | 8p12 | 607102 | 12796 | GC11M032365 | Azoospermia |
ZMYND15 | Zinc-finger MYND-type containing 15 | 17p13.2 | 614312 | 20997 | GC17P004740 | Azoospermia |
Table data source[1] (table 1) Links: fertilization | spermatozoa | testis | Male Infertility Genes | Female Infertility Genes | oocyte | ovary | Genetic Abnormalities | ART |
- ↑ Harper JC, Aittomäki K, Borry P, Cornel MC, de Wert G, Dondorp W, Geraedts J, Gianaroli L, Ketterson K, Liebaers I, Lundin K, Mertes H, Morris M, Pennings G, Sermon K, Spits C, Soini S, van Montfoort APA, Veiga A, Vermeesch JR, Viville S & Macek M. (2018). Recent developments in genetics and medically assisted reproduction: from research to clinical applications. Eur. J. Hum. Genet. , 26, 12-33. PMID: 29199274 DOI.