Talk:Book - The Hormones in Human Reproduction

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INDEX

Abortion, causes of, 128; treatment with progesterone, 128, 129

Adler, L., 81, 108

Adrenal gland, androgenic hormone in, 234; estrogen in, 93; progesterone in, 117; removal of, 172, 229

Adrenalin, see Epinephrin

Afterbirth, see Placenta

Agassiz, Louis, 17

Albumen, of egg, 40

Allen, B. M., 141

Allen, Edgar, 37, 73, 82-86, 88, 100, 159, 160-1G2, 172, 254

Allen, W. M., 104, 112, 114-llG, 118120. 125, 182, 194, 253

de Allende, In^s L. C, 74, 158, 211

Alligators, effect of estrogen, 94

Amphibians, mating, 23

Ancel, P., 107, 108, 110, 111, 114, 235

Andersen, Dorothy H., 47

Androgenic hormones, assay, 236; chemistry, 233, 234, 250, 251 ; deficiency, 237, 238; discovery, 232; effects, 237, 254-257; international unit, 236; isolation, 233; local action, 236; oral, 269; pellets, 236; source of, in testis, 236; treatment with, 237-239; in urine, 234

Androstane, 250

Androsterone, 234, 236, 250

Anovulatory cycles, 155-159

Anovulatory menstruation, 155-159, 168, 169

Anthracene, 245, 246

Apes, anthropoid, 135

Aquatic environment, of germ cells, 217

Arbacia, see Sea urchin

Arey, L. B., 135, 136

Aristotle, 69

Arrhenius, S., 138

Arteries, coiled (or spiral), see Blood vessels

Aschheim, S., 85, 141, 202

Aschheim-Zondek test, 202


Aschner, B., 81

Ascidians, reproduction, 22

Asdell, S. A., 68, 254, 262

Atlee, J. L., 160

Atlee, W. L., 160

Atrophy, castrate, in female, 79, 80,

124; effect of estrogens upon, 94;

in male, 237 Autolytus, fission, 6

Baboon, cycle, 262

Bachmann, W. E., 87

von Baer, K. E., 34

Ball, Josephine, 97

Banting, Sir Frederick, 126

Bartelmez, G. W., 148-151, 267

Bates, R. W., 211

Battey, Robert, his operation, 160, 161

Berthold, A. A., 228-230, 232, 268

Best, Charles, 126

Birds, mating, 23

Birth, see Parturition

Bisexual reproduction, see Reproduction

Bison, estrus, 63

Blood vessels of uterus, 150-153, 158, 169-171, 264, 265

Bloor, W. R., 112

Boling, J. L., 39

Bonellia, 26

Bonsnes, R. W., 268

Born, G., 104, 105

Bouin, P., 104, 107, 108, 110, 111, 114, 210, 235

Boyle, Robert, 54

Breast, see Mammary gland

Breeding seasons, 64

Broedel, Max, opposite p. 34

Brouha, L., 143, 181, 182

Browne, J. S. V., 120, 185

Browne, Sir Thomas, 11

Brown-S^quard, C.-E., 229, 230

Budding, reproduction by, 4, 5, 7, 8

Bulls, pregnanediol secreted by, 260

Burdick, H. O., 45, 48

Burns, R. K., 255, 256, 257


Burrows, Harold, 254, 264 Butenandt, A., 86, 104, 115, 116, 232, 233

Cancer, relation of estrogenic hormones to, 99-100

Capon test, 236

Carcinogenic substances, 99

Casanova de Seingalt, Giovanni Jacopo, 29

Casserius, Julius, opposite p. 143; 200

Castrate atrophy, see Atrophy, castrate

Castration, of female, 79, 96; of male, 228

Catlin, George, 63

Cervix (of uterus), 54

Chimpanzee, pregnanediol excreted by, 121

Cholesterol, 116, 246

Chromosomes, 21, 22, 227

Clark, L. B., 254

Clarke, F. J., 129

Clauberg, C, 184

Cloaca, 23, 24

Clone, 12, 13

Coiled arteries, see Blood vessels

Cole, Wayne, 87

Collip, J. B., 126

Comb test, see Capon test

Conjugation, 13

Corals, reproduction, 22

Corpus luteum, color, 43; degeneration, 44, 139, 145, 148; discovery of function, 106-111; effect on endometrium, 107-111; formation, 41, 42; as gland of internal secretion, 103; human, 43; life of, 44; in menstrual cycle, 146; necessary for implantation of embryo. 111, 257-259; how long necessary in pregnancy, 125, 260, 261 ; number of cells in, 186; number of c. 1. in various species, 43; rate of secretion, 180-187; effects of removal, 106; in reproductive cycle, 66, 139; effect on sex urge in guinea pig, 98; structure, 43; volume in rabbit, sow, human, 182-184


Corpus luteum hormone, see Progesterone

Cothurnia, reproduction, 3, 4, 12

Courrier, R., 102, 254, 259

Cow, cycle, 65; proestrous bleeding, 174

Crawford, Jane, 79

Crop glands, 211, 212

Crop milk, 211

Cryptorchidism, 222, 235

Cycle, menstrual, 69, 70, 262; anovulatory, in monkey, 155-159; events of, 145-148; in human, 159; hypothetical explanation, 166169; modern concept, 172, 173; theories about, 154, 265-266; see also Menstruation

Cycle, reproductive, in animals, 64, 65, 139; cause of, 74, 75; events of, in non-menstruating animals, 144; events of, in menstruating animals, 145-148; in human, 69; length of, in various species, 65, 138 ; nature of, 68 ; physiology of, 139-145; of sow, 65-67; variations of, 68

Cyclopentenophenanthrene, 246

Dalgaard, J., 266

D'Amour, F. E., 86

Daron, G. H., 150, 267

David, K., 233

Deanesly, Ruth, 91, 193

Deciduomata, 109, 110, 114

Dedalus, Stephen, 29

De Jongh, S. E., 86

Dickinson, R. L., 60

Didusch, J. F., 45

Diethyl stilbestrol, see stilbestrol

Dingemanse, E., 86, 233

Dionne quintuplets, 43

Dodds, E. C, 89

Dog, cycle, 65 ; proestrous bleeding, 174, 175

Dog-fish, 25

Doisy, E. A., 73, 83, 84, 86, 88, 250

Domm, L. V., 232

Dorfman, R. L., 203

Ductless glands, see Internal secretion, glands of

Dysmenorrhea, 129-131

Egg, see Ovum

Einstein, Albert, 62

Elephant shrew, 262

Embryo, attachment (implantation), 57, 257-259; aquatic environment, 217; human, 146, 148; of mammals, 48, 51, 66, 57; metabolism, 201

Emerson, Ralph Waldo, 62, 216

Endocrine glands, see Internal Secretion, glands of

Endometrium, in cycle of non-menstruating animals, 144, 145; of menstruating animals, 146-159; effects of progesterone on, 107113; function, 64; grafts in eye, 151, 152; structure, 50-54

Engle, E. T., 164, 165, 185, 191

Epididymis, 220, 224-226

Epinephrin (Adrenalin), as drug, 126; effect on blood vessels, 28; effect on uterine muscle, 123; not implicated in menstruation, 172

Epithelium, germinal, 34

Equilenin, 86, 88, 249

Esters of estrogenic hormones, 88

Estradiol, 86, 88, 248, 249

Estrane, 244, 245, 247

Estratriene, 247

Estrin, 86

Estrin-deprivation bleeding, 161172, 189-191

Estrin-deprivation hypothesis, 162167

Estriol, 86, 249

Estrogen, see Estrogenic hormones

Estrogenic hormones, action of, 939Q, 254, 257; administration, 91, 92; in adrenal gland, 98; in blood, 84; relation to cancer, 99, 100; chemistry, 86-89, 247-249; in corpus luteum, 84; discovery, 8286; esters, 88; in Graafian follicle, 83, 84; effect on growth of uterus, 80, 82, 85, 93-95, 204, 205; effect on mammary gland, 95, 208, 213; names, 84, 86; output, daily, of monkey, 192; output of woman, 90, 194, 268; in parturition, 206; pellets, 91, 92; in placenta, 85, 92;


in plants, 84; potency, 90; proestrous bleeding induced by, 176; pubertal changes induced by, 9496; purification, 85, 86; rate of secretion, 189-194; in reproductive cycle, 75, 96-98; series of estrogenic compounds, 88; effects in sex urge, 97, 98; source of in ovary, 34, 92; effects on uterine muscle, 124, 125, 205; in treatment of menstrual disorders, 98, 99; in urine, 85, 203; effects on vagina, 93

Estrone, administration, 91; chemistry, 86, 87, 248; international unit, 90; isolation, 86; name, 86; potency, 90; synthesis, 87, 88

Estrous cycle, see Cycle

Estrus, 63, 64, 69, 70

Ethinyl estradiol, 91

Ethinyl testosterone, 260

Eunuchoid state, 238, 239

Evans, H. M., 69, 73; opposite p. 74; 141, 156

Excretion, of androgenic hormone, 234; of estrogenic hormone, 86; of progesterone, 120, 121, 185, 204

Experimental menstruation, see Menstruation, experimental

Fallopian tube, see Oviduct

Fallopio, Gabriele, 45

Father, biological utility, 25, 26

Fellner, O., 82, 84, 85

Fels, E., 104, 115

Female sex hormone, see Estrogenic hormones

Fertilization, in Hydra, 10; in general, 16; in sea urchin, 17; in mammals, 55, 66; meaning of, 18

Fevold, H., 104, 113-115

Fieser, L. F., 243

Fishes, mating in, 23; viviparous, 24, 25

Fission, reproduction by, longitudinal, 3; transverse, 6

Follicle, ovarian (Graafian), 33-35,


12, 66

Follicle fluid, nature of, 83; estrogenic hormone in, 84

Follicle-stimulating hormone, 263, 264

Forbes, T. R., 94

Fraenkel, L., 104-106, 110, 111, 164, 156

Frank, R. T., 82, 84, 85, 104

Freind, John, 134

Freud, J., 233

Friedman, M. H., his test, 202

Friedmann, E., 243

FSH, see Follicle-stimulating hormone

Funk, Casimir, 232

Gardner, W. U., 100

Genetics, 21, 22

Germ cells, 15, 22; their aquatic environment, 217; see also Ovum, sperm cell

Germinal epithelium, 34

Gersh, Isidor, opposite p, 218

Geschickter, C. F., 100

Gestation, 24, 26; length of, 26

Gey, G. O., 202

Gillman, J., 262

Gonadotrophic hormones, of pituitary gland, 262-264; in cycle, 141 ; dual nature, 201; at puberty, 95; effects on testes, 221, 222

Gonadotrophic hormones, of placenta, 201-203, 262-264

Gonads, 22; see also Ovary, Testis

de Graaf, Regner, 33, 35, 44

Graafian follicle, see Follicle

Grafts, of endometrium in eye, 161, 152, 166; of ovary, 80; of testis, 231, 236

Granulosa, 34

Greep, R. O., 166, 191

Gregory, P. W., 56

Grueter, F., 210, 212

Guinea pig, cycle, 72, 73 ; relaxation of pelvis, 113; vaginal closure membrane, 68, 72

Gunn, A. L., 138

Gunn, D. L., 138

Gustavson, R. G., 86

Guttmacher, A. F., 22


Haggstrom, P., 41

Halban, J., 80, 81, 86

Hamilton, J. B., 238

Hammond, John, 37

Harrow, Benjamin, 232

Hartman, C. G., 37, 44, 67, 74, 100, 148, 150, 158, 171, 175, 198, 260

Hartman's sign, 175

Harvey, Ethel Browne, 17; opposite pp. 18, 19; 56

Harvey, William, 32

Heape, Walter, 63, 155, 156, 174

Heredity, 21, 22

Herrmann, E., 82, 84, 85, 112, 118

Hertig, A. T., 57, 148

Hess, M. N., 254

Heuser, C. H., 57

Hill, R. T., 37

Hisaw, F. L„ 104, 113-116, 120, 143, 164-166, 169, 191

Hitschmann, F., 108

Hormones, 27; see also Androgenic, Estrogenic, Gonadotrophic and Lactogenic Hormones, Progesterone

Huber, G. C, 45, 219

Hubrecht, A. A. W., 155, 166

Huxley, Julian, 8, 22

Hydra, eg^, 9; sperm cell, 10; reproduction by budding, 7; testis, 10, 217

Hypophysis, see Pituitary gland

Iglesias, Rigoberto, 100

Implantation, of embryo, 57-59, 257259

Inductors, embryonic, 257

Insulin, 28, 126

Intermenstrual bleeding, 175

International unit, of estrone, 90; of progesterone, 117; of androsterone, 236

Internal secretion, glands of, 27, 28

Interstitial cellp of testis, 224, 231, 235

Inunction, administration of hormones by, 91, 236

Iscovesco, H., 81, 84, 86

Java macaque, 138

Jenkin, P. M., 138 Jennings, H. S., 14 Joublot, S., 181 Juhn, Mary, 232

Kaiser, Irwin H., 265 Kamm, Oliver, 87 Kaufmann, C, 184 Kelvin, Lord, 178, 195 Kipling, Rudyard, 26 Knauer, E., 80, 81 Knaus, H., 122-124 Kober, S., 86 Koch, F. C, 232, 234, 251 Kramer, T. C, 37

Lactation, experimental, 210; pituitary hormone for, 95, 207-214; see also Mammary gland

Laqueur, E., 86, 233

Lataste, F., 72

Laucius, J. F., 87

League of Nations, 90, 117, 236

Leonard, S. L., 104, 143

Leonard, William Ellery, 2

Lewis, C. Day, 63

Lewis, Sinclair, 129

Lewis, W. H., 38, 45, 47, 56, 258

LH, see Luteinizing hormone

Lipschutz, A., 100

Lister, Joseph, 160

Locust, 17-year, 65, 138

Loeb, Jacques, 18

Loeb, Leo, 83, 104, 109-111, 114

Loewe, S., 85, 232

Long, C. H. N., 268

Long, J. A., 69, 73; opposite p. 74; 156

Lubin, Samuel, 129

Ludwig, C, 79

Luteinizing hormone, 268

Lyons, W. R., 268

MaeCorquodale, D. W., 88 McDowell, Ephraim, 79, 160 McGee, L. C, 232 McGregor, T. N., 129 McLeod, J. J. R., 126 Macaque, see Java macaque; Monkeys


Male hormones, see Androgenic hormones

Malpas, Percy, 129

Mammary gland, effects of hormones on, 95, 209-213 ; embryonic origin, 212; effect of pituitary hormone, 207-214; growth, at puberty, 80, 207, 208; in pregnancy, 208; structure, 208

Mare, gonadotrophic hormone in, 203, 262; equilenin, 249

Markee, J. E., 150-152, 158, 165, 169, 258

Marker, R. E., 87

Marshall, F. H. A., 175

Mason, K. E., opposite p. 219

Mating, 23

Medusa (jelly fish), reproduction by budding, 7

Membranes, fetal, 57, 58

Mencken, Henry, 226

Menopausal symptoms, treatment with estrogens, 99

Menstrual cycle, see Cycle, menstrual

Menstrual disorders, treatment with estrogens, 98, 127; treatment with progesterone, 127, 129-132; various degrees of, 173

Menstruation, age of onset, 137; anovulatory, 155-159, 168, 169; in apes, 135, 137; breakdown of endometrium in, 148; cause of, immediate, 169-173, 265-269; es~ trin-deprivation hypothesis, 162167; experimental, 159; in eyegrafts, 151, 152, 165, 166; "German" theory of, 154-157, 159, 161 ; in girls, 136, 137; occurrence in higher primates only, 69, 70, 135, 261-262; periodicity, 135-137; non-relation to moon, 137, 138; in monkeys, 137, 138, 155-158, 261262; significance of, 174-176; theory of, 154-158, 162-172, 264267; see also Cycle, menstrual; Menstrual disorders

Meyer, Robert, 154-156

Meyer, Roland K,, 104, 113, 143, 175

Milton, John, 11

Miscarriage, aee Abortion

MoUusks, reproduction, 24

Monkeys, cycle of Java macaque, 138; cycle of Rhesus, 137; experimental menstruation in, 159, 161-167; endometrial grafts in, 151 ; gonadotrophic hormones in, 202; menstruation in, 137, 138, 165-158; New World Monkeys, absence of external menstruation, 153; rate of secretion of estrogen, 189-194; sex skin, 190, 193

"Monkey glands" (testes), 231

Moon, relation to reproductive cycle and menstruation, 64, 137, 138

Moore, C. R., 143, 222, 223, 232, 237, 255, 256

Morula, 18, 66

Mouse, see Rat and Mouse

Muller, R. H., 89

Mulligan, E. W., 160, 161

Muscle, of uterus, see Uterine muscle

Needham, Joseph, 257 Nervous system, 27 Nicholas, J. S., 258 Nucleus, of ovum, 17, 18, 19, 21, 89; of sperm cell, 18, 19, 21

Oakwood, T. S., 87

Obelia, reproduction, 7

Oestrus (and related words), tee Estrus, etc.

Okkels, H., 266-267

Opossum, 256

Organizers, 257

Ovary, dependence on pituitary gland, 75, 141, 263; dimensions, 33; extracts of, 81, 82; grafts of, 80; human, 33; internal secretion first suggested, 80, 81 ; of mouse, 33; eflFects of removal, 79; removal followed by uterine bleeding, 160, 161; removal during pregnancy, 125, 204, 260-261; structure, 34, 35; of whale, 33

Oviduct, 20, 22, 44, 45, 94

Ovulation, in animals, 37; in cycle of sow, 66, 68 ; in menstrual cycle,


148, 149; in reproductive cycle, 139

Ovum, of birds, 24, 33, 39; defined, 9; discharge of («ee Ovulation); discovery, 33, 34; division, in sea urchin, 18; division, in mammals, 66, 67; fertilization, 10, 16-18, 65, ^^\ formation, 34, 36; human, 34, 36, 37-39; of Hydra, 9; of mammals, 20, 24, 34, 36, 87-40; of monkey, 38; number of, in ovary, 41 ; of reptiles, 24 ; of sea urchin, 17; size of, 37, 40; of sow, 38, 39; specifications, 8; transportation, 24, 46-48, 66; of turtle, 24; unfertilized, fate of, 40, 41; yolk, 33, 39,40

Oyster, embryos, 24

Palolo, 64, 138, 254

Pancreas, 28

Papanicolaou, G. N., 72, 82, 166

Paramecium, mating reactions, 14

Paradoxical effects, of gonadal hormones, 257

Parker, G. H., 45

Parkes, A. S., 91, 92, 193, 208, 210

Parthenogenesis, artificial, 18-20; natural, 20

Parturition, 206, 207

Pellets, of androgenic hormones, 193, 236; of estrogenic hormones, 91, 92, 192, 193

Penis, 24

Phenanthrene, 246

Pincus, Gregory, 20, 21, 48, 181

Pituitary gland, anterior lobe, 141; in cycle, 75; deficiency in male, 237; effect on crop gland of pigeon, 211, 212; effect on descent of testes, 222, 223; gonadotrophic hormones, 95, 141, 262-264; lactation hormones, 95, 207-214; effect on ovary, 95, 141 ; effect on oviduct of toad, 211, 212; at puberty, 95; structure, 141; effect on testis, 222

Pituitrin, effect on uterine muscle, 123; not involved in menstruation, 171

Placenta, defined, 25; of dog-fish, 25; estriol in, 249; estrogenic hormones in, 203, 204; gonadotrophic hormones in, 201, 202, 262-264; progesterone in, 117, 126, 204; structure, 59, 200, 201

Plants, estrogens in, 84; fertilization, 22, 23

Poehl, A. v., 230

Postpartum pain, 129

Pratt, J. P., 185

Pregnancy, hormones in, 199; maintenance, 114, 127, 128, 199; tests for, 202, 203

Pregnane, 251

Pregnanediol, 120, 121, 185, 204, 252, 260; glycuronidate, 121, 253

Pregneninolone, 260, 261

Premenstrual state, 146, 157; see also Progestational proliferation

Prenant, L. A., 44, 103-105

Price, Dorothy, 143

Primates, 70, 261

Proestrous bleeding, 174, 176

Progestational proliferation, in various animals, 108; in cycle, 144, 146; produced by corpus luteum, 108, 111-114; defined, 107; in menstrual cycle, 146; in rabbit, 113; in monkey, 114

Progesterone, administration, 117, 118, 260; in adrenal gland, 117; chemistry, 116, 251, 252; in cycle of sow, 66; discovery, 103-115; effect on endometrium, 113, 114, 120: in estrous cycle, 144; in experimental menstruation, 164169; difficulties in isolating, 118120; excreted as pregnanediol, 120, 260; relative ineffectiveness in immature animals, 118-120; inhibition of estrin-deprivation bleeding and menstruation, 164; international unit, 117; isolation, 112-115; in lactation, 210, 212, 213; in menstrual cycle, 146, 167, 169; molecular weight, 186; name, 103, 117; in placenta, 117, 126, 204; maintenance of pregnancy, 114, 127, 128; potency, 117; puri


fication, 115; rate of secretion, 180-187, 268; relation to sex urge in guinea pig, 98; sources of, 117; synthesis, 116, 253; treatment with, 126-132, 186, 261; effects on uterine muscle, 122-125, 128, 205 ; utilization of by uterus, 188

Progesterone-deprivation bleeding, 164, 165, 169

Progestin, 116, 117; see a/jo Progesterone

Prolactin, 211-213, 268

Prolan, 264

Prostate gland, 226, 227

Protozoa, reproduction in, 3-5, 1314

Puberty, growth of reproductive organs at, 80; estrogenic hormones in, 95, 96 ; growth of mammary glands, 207, 208; development of male secondary sex characteristics, 227

Quintuplets, 43 Quiring, D. P., 268, 269

Rabbit, embryos, 105; dependence of embryos upon corpus luteum, 110, 111; ovulation described, 37; ovulation not spontaneous, 68, 106

Rabelais, Francois, 78

Rat and mouse, cycle, 65, 68-71, 73, 74; test of estrogenic hormones, 83

Reather, C. F., 67

Rejuvenation, 230, 231

Relaxin, 113, 114, 120

Reproduction, bisexual, 11, 14, 15; by budding, 4, 5, 7; by eggs, 8, 9; by longitudinal fission, 3; by multiple fission, 5; by transverse fission, 5; sexual, 10, 20; by spores, 5

Reproductive cycle, see Cycle

Reptiles, mating, 23

Rever, A. G., xi

Reynolds, S. R. M., 49, 124, 126, 204-206

Rhesus monkey, see Monkey


{ 279 }


INDEX


Riddle, Oscar, 211 Robinson, Arthur, 83 Rock, John, 67 Runner, M. N., 258 Ruschig, H., 115 Ruzicka, L., 233

Safe period, 149

Saiki, Seiichi, 176

Scheinfeld, A. M., 22

Schickele, G., 81

Schiller, Sara, 268

Schlegel, J. V., 266

Schroeder, R., 154, 166

Schweitzer, Malvina, 22

Scrotum, 218, 222, 223

Scytomonas, mating, 13

Sea urchin, reproduction, 16, 17, 18-22

Seeger-Jones, G., 268

Seminal duct, 225, 231

Seminal fluid, 224, 226

Seminal vesicle, 225

Seminiferous tubules, 218, 235, 236

Sex, bisexuality, 11, 15; nature of, 10, 11; in human beings, 26

Sex characteristics, secondary, female, 96, 255; male, 227, 228, 255

Sex skin, 190, 193

Sex organs, embryonic, effect of hormones on, 254-260

Sex urge, in animals and man, 28, 70; effect of estrogenic hormones on, 97, 98; relation of progesterone to, 98; effect of androgenic hormones, 237

Shapiro, H., 20

Shelesnyak, M. C, 164, 165

Shnrr, kphraim, 74, 158

Shrew, see Elephant shrew

Simonnet, H., 143

Slotta, K., 104, 115

Smith, G. Van S., 172, 267, 268

Smith, Olive W., 172, 267, 268

Smith, P. E., 141, 164, 166, 171, 186, 222

Snyder, F. F., 46

Sobotka, Harry, 243

Sow, eggs, 38, 39; events of cycle in, 65-67


Spermatogenesis, 221, 222, 235, 236

Sperm cell, in fertilization, 17; of Hydra, 10; in general, 15; of rat, 220; of man, 220; of sea urchin, 17; transmission to fem.ale, 23, 24; transportation within male, 224

Spermine, 230

Spiral arteries, see Blood vessels

Sponges, reproduction by budding, 7, 22

Stallion, excretion of estrogenic hormone by, 85

Steinach, E., 231, 235

Steroids, Sterols, 86, 87, 116, 246

Stewart, C. P., 129

Stieve, H., 200, 204

Stigmasterol, 253

Stilbestrol (diethyl stilbestrol), 86, 89, 91

Stockard, C. R., 22, 72, 82, 156

Stover, R. F., 185

Streeter, G. L., 57

Strieker, P., 210, 212

Taylor, Hugh, 89

Te Linde, R. W., 268

Testis, descent, 222, 223; double function, 217; grafts of, 231, 235; hormone (see also Androgenic hormones), 228-240; of Hydra, 10; interstitial cells, 224, 231, 235; effect of pituitary hormones on, 221, 222; structure, 218-220; temperature, 222, 223

Testosterone, 234, 251

Tests, Allen-Doisy, 83; AschheimZondek, 202; capon (comb) 236; Friedman, 202; rabbit test for progesterone, 112, 232; vaginal test, 83

Thayer, S. A., 88

Theca interna, 34

Theelin, see Estrone

Thyroid gland, 28

Tice, P, S., opposite pp. 8, 9

Toxopneustes, see Sea urchin

Transportation of ovum and sperm cell; see Ovum, Sperm cell

Triplets, 43


{ 280 }


INDEX


Trophoblast, 201

Tumors of uterus, decidual, 109, 110, 114; fibroids of guinea pig, produced by estrogens, 100

Turner, C. W., 209, 213

Twins, 43

Umbilical cord, 200

Unit, see International unit

Urethra, 226

Urine, androgenic hormones in, 234; estrogenic hormones in, 85, 86-203; gonadotrophic hormones in, 202-204, 262-264; prpgnanediol in, 120, 121, 185, 204

Uterine muscle, growth in pregnancy, 204; effect of estrogenic hormones on, 93, 124; 204, 205; effects of progesterone on, 122, 123, 125, 128, 204, 205

Uterus, defined, 25; distention in pregnancy, 205; form, in various animals, 60, 51; growth of, caused by estrogenic hormones, 80, 82, 85, 93-95, 204, 205; preparation for implantation of embryo, 59; structure, 48-54, 150; tumors of, 100, 109, 110, 114; utilization of progesterone, 188; see also Blood vessels. Endometrium, Uterine muscle

Vagina, defined, 24; in estrous cycle, 71; of guinea pig, 72; of mouse, 82 ; of rat, 73, 74 ; of monkey, 74; structure, 50, 64, 55

Vaginal closure membrane, 68, 72

Vaginal test, 72, 82, 83


Van der Horst, C. J., 262 Van Herwerden, M. A., 155, 156 Van Wagenen, Gertrude, 203 Vargas Fernandez, Luis, 100 Vas deferens, see Seminal duct Vasectomy (Steinach operation),

231 Venning, Ethel H., 120, 186 Villi, of placenta, 200, 201 Virgil, 63

Voronoff, Serge, 230 Voss, S. H., 232

Walton, Arthur, 87 Weichert, C. K., 104, 113, 114 Welch, W, H., 161 Wells, G. P., 8, 22 Wells, H. G., 8, 22 Westphal, U., 115 Whale, ovary, size of, 33 ; progesterone in, 117 White, Abraham, 268 Whitman, Walt, 198 Whitney, Rae, 48 Wiesbader, Hans, 185 Wilds, A. L., 87 Wilson, E. B., 17 Wintersteiner, Oskar, 116 Wislocki, G. B., opposite p. 34 Wright, Elsie S., 47

Yolk of egg, 83, 39, 40 Young, W. C, 97

Zondek, B., 85, 141, 163, 202 Zuckerman, S., 162, 166, 168, 176, 190, .262