Talk:2010 BGD Practical 12 - Neonatal
From Embryology
A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Liggins GC, Howie RN. Pediatrics. 1972 Oct;50(4):515-25. No abstract available. PMID: 4561295
Antenatal glucocorticoid therapy administered to women at risk for preterm delivery (PTD) reduced the incidence of respiratory distress syndrome (RDS) and mortality in their offspring. Antenatal glucocorticoid therapy leads to improvement in neonatal lung function by enhancing cell development (Type 1 and 2 alveolar cell maturation) and by inducing lung enzymes that play a role in biochemical maturation.
