Paper - The Sexual Cycle in the Human Female as revealed by Vaginal Smears

Embryology - 2 Jun 2024 Expand to Translate
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Papanicolaou GN. The Sexual Cycle in the Human Female as revealed by Vaginal Smears. Am J Anat. 1933;52: 519–637.

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These are currently some of the plates from the historic paper by George Papanicolaou (1883 – 1962) the pathologist who developed the diagnostic "Pap smear" test named after him. Originally a Greek clinician (Georgios Nikolaou Papanikolaou) he travelled throughout Europe before becoming in 1913 an American researcher. His first studies were in other species (Guinea-Pig) before extending the studies onto humans. This paper described the appearance of normal cell smears during the different stages of the menstrual cycle. The true value of the "Pap smear" test was the identification of abnormal cells associated with cytopathology of cancer of the cervix.

The original black and white photomicrographs were hand-coloured by the author to match his microscopic observations.

Historic Embryology - Menstrual
1839 Corpus Luteum Structure \| 1851 Corpus Luteum \| 1933 Pap Smear \| 1937 Corpus Luteum Hormone \| 1942 Human Reproduction Hormones \| 1951 Corpus Luteum \| 1969 Ultrastructure of Development and Regression \| 1969 Ultrastructure during Pregnancy

Plates

Plate 9

Drawings of various types of cells found in normal human vaginal smears.

36 to 60 Cells from human vaginal smears at different stages of the normal menstrual cycle.

Plate 10

Drawings of various types of cells found in normal human vaginal smears.

61 to 68 Cells from human vaginal smears at different stagesrof the normal menstrual cycle.
69 to 79 Characteristic types of cells found in human vaginal smears during pregnancy.
80 Normal mononuclears during menstruation.
81 Large mononuclears found in post—partum.
82 to 84 Cliaraeteristic types of cells found in postpartum.

Cite this page: Hill, M.A. (2024, June 2) Embryology Paper - The Sexual Cycle in the Human Female as revealed by Vaginal Smears. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_The_Sexual_Cycle_in_the_Human_Female_as_revealed_by_Vaginal_Smears

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