File:Mouse E9 Foxf1.jpg

Figure 5. Analysis of Foxf1 expression in adrimycin treated and control embryos shows abnormal localisation in the foregut associated mesenchyme in the vicinity of ectopic notochord branches. Control (A–F) and adriamycin treated embryos (G–L) represented by virtual, sagittal (A,D,H,K), coronal (B,E,I,L) and transverse (C,F,G,J) sections of OPT reconstructions following whole mount in situ hybridisation with Foxf1 antisense probe show expression in the floor plate, notochord, foregut endoderm and associated mesenchyme. Blue dotted lines indicate the planes of coronal and transverse sections. Red arrow heads on transverse sections of control embryos at E9 and E11 (C, F) indicate the ventral bias in distribution of Foxf1 transcripts in the foregut mesenchyme. Note the absence of this pattern in treated embryos (G, J). fp; floor plate, nc; notochord, fg; foregut, lb; lung bud.

Links: Image - E9 Foxf1 | Image - E11 Foxf1Image 1 - E11 Notochord | Image 2 - E11 Notochord | Image 3 - E11 Notochord | Image 4 - E11 Notochord | Notochord | Mouse Development | Category:Mouse E11.0 | Image- Mouse embryo E11 and tomography | Image - Mouse embryo E11 tomography | OMIM FORKHEAD BOX A2

Reference

<pubmed>22132119</pubmed>| PLoS One.

Copyright

© 2011 Hajduk et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 5. doi:10.1371/journal.pone.0027635.g005 Panel cropped from full figure, resized and relabelled.