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Genomic and Size distribution of Human Nucleolus-Associated Chromatin Domains (NADs)

(A) Distribution of nucleolus-associated chromatin domains (NADs) together with satellite repeats along human chromosomes. Note that the p-arms of the five acrocentric chromosomes (13, 14, 15, 21 and 22) were not analysed because they are not assembled in the hg18 genome build. NADs are labeled with red, satellite repeats with deep blue, centromeres with yellow and chromosomes with light blue

(B) Histogram of NAD sizes; median = 749 kb; a total of 97 NADs were identified.

doi:10.1371/journal.pgen.1000889.g002


Citation: Németh A, Conesa A, Santoyo-Lopez J, Medina I, Montaner D, et al. (2010) Initial Genomics of the Human Nucleolus. PLoS Genet 6(3): e1000889. doi:10.1371/journal.pgen.1000889

Editor: Asifa Akhtar, Max-Planck-Institute of Immunobiology, Germany

Received: November 18, 2009; Accepted: March 1, 2010; Published: March 26, 2010

Copyright: © 2010 Németh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Figure 2. Journal.pgen.1000889.g002.tiff

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