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- 23:10, 14 September 2010 Z3254433 talk contribs uploaded File:Karyotype Down syndrome.gif (Trisomy 21 (down syndrome) a chromosomal abnormality that may be detected by maternal serum alpha fetoprotein screening. z3254433 Creative commons licence 2. Licence Terms 2.1 The Licensor hereby grants to You a worldwide, royalty-free, non-exclusive, )