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- 03:55, 26 April 2010 S8600021 talk contribs uploaded File:Mouse- hindlimb buds Shh expression.jpg (Shh expression in wild-type and Hand2 deficient hindlimb buds at E10.75 (37 somites). Excerpt from Figure 2. Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. Galli A, Robay D, Os)