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- 00:57, 29 March 2010 S8600021 talk contribs uploaded File:Sea Urchin-endomesoderm induction.png (Gene Regulatory Networks Underlying Endomesoderm Induction (A) The micromere determinant Pmar1 (circled in red) activates the PMC-GRN in micromere progeny and is sufficient for micromere-derived endomesoderm-inducing signals. The E-EM/En-GRNs (up to 17 h)