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- 21:42, 6 March 2012 Z8600021 talk contribs uploaded File:Polycystic kidney disease cartoon.jpg (==Cyst formation at the level of the cell, nephron, and kidney== * Defects in the genes encoding PC1 or PC2 lead to aberrant gene transcription, cell proliferation, and ion secretion, which in turn result in the formation of fluid-filled cysts. * As cys)