File:Mechanism of tetrabenazine.jpg
Mechanism_of_tetrabenazine.jpg (600 × 459 pixels, file size: 33 KB, MIME type: image/jpeg)
Mechanism of tetrabenazine inhibition
VMAT2 is the only transporter that transports dopamine from the cytoplasm into synaptic vesicles for storage and eventual release.[92] By inhibiting VMAT2, dopamine will not be packaged into vesicles and hence, unable to travel across the synaptic cleft. Tetrabenazine also binds and inhibit to dopamine receptors. This suppresses the amount of dopamine binding to the dopamine receptor located at the post synaptic nerve terminal. Thus, the neurones will not be stimulated and no cascade for the inducement of kinetic movements will be triggered.
Based upon Tetrabenazine for the Treatment of Huntington’s Chorea
Drawn & uploaded by Z3389806.
Beginning six months after publication, I (Z3389806) grant the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 19:43, 20 September 2011 | 600 × 459 (33 KB) | Z3389806 (talk | contribs) | Reverted to version as of 09:41, 20 September 2011 | |
19:43, 20 September 2011 | 600 × 459 (33 KB) | Z3389806 (talk | contribs) | ==Mechanism of tetrabenazine inhibition== VMAT2 is the only transporter that transports dopamine from the cytoplasm into synaptic vesicles for storage and eventual release.[92] By inhibiting VMAT2, dopamine will not be packaged into vesicles and hence, u | ||
19:41, 20 September 2011 | 600 × 459 (33 KB) | Z3389806 (talk | contribs) | ==Mechanism of tetrabenazine inhibition== VMAT2 is the only transporter that transports dopamine from the cytoplasm into synaptic vesicles for storage and eventual release.[92] By inhibiting VMAT2, dopamine will not be packaged into vesicles and hence, u | ||
20:14, 19 September 2011 | 2,448 × 1,872 (221 KB) | Z3389806 (talk | contribs) | ==Mechanism of tetrabenazine inhibition== VMAT2 is the only transporter that transports dopamine from the cytoplasm into synaptic vesicles for storage and eventual release.[92] By inhibiting VMAT2, dopamine will not be packaged into vesicles and hence, u |
You cannot overwrite this file.
File usage
The following 3 pages use this file: