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Human Seminiferious Tubule - Non-obstructive azoospermia and Obstructive azoospermia

Two main forms identified as:

  1. Obstructive azoospermia (OA) - blockage of duct network
  2. Non-obstructive azoospermia (NOA) - ADP-ribosyltransferase 3 gene (ART3) recently described as a susceptibility gene.

Okada H, Tajima A, Shichiri K, Tanaka A, Tanaka K, Inoue I. Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility. PLoS Genet. 2008 Feb;4(2):e26. PMID: 18266473

Citation: Okada H, Tajima A, Shichiri K, Tanaka A, Tanaka K, et al. (2008) Genome-Wide Expression of Azoospermia Testes Demonstrates a Specific Profile and Implicates ART3 in Genetic Susceptibility. PLoS Genet 4(2): e26. doi:10.1371/journal.pgen.0040026

Editor: Emmanouil T. Dermitzakis, The Wellcome Trust Sanger Institute, United Kingdom

Received: July 31, 2007; Accepted: December 13, 2007; Published: February 8, 2008

Copyright: © 2008 Okada et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current01:08, 10 Mayıs 2010Thumbnail for version as of 01:08, 10 Mayıs 2010768 × 554 (77 KB)S8600021 (talk | contribs)Human Seminiferious Tubule - Non-obstructive azoospermia and Obstructive azoospermia Two main forms identified as: # Obstructive azoospermia (OA) - blockage of duct network # Non-obstructive azoospermia (NOA) - ADP-ribosyltransferase 3 gene (ART3) recent