Jacob's syndrome

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Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose.
 ICD-11
LD52.1 Male with double or multiple Y
A condition affecting males, caused by the presence of supernumerary Y chromosomes. This condition is asymptomatic. Confirmation is through observation of supernumerary Y chromosomes by karyotyping.

Introduction

Jacob's syndrome (47 XYY syndrome, XYY syndrome) is a rare chromosomal disorder caused by the presence of an extra Y chromosome. Normally, males have 46 chromosomes including one X and one Y chromosome. Males with XYY syndrome have 47 chromosomes, two of which are Y chromosomes.



Cite this page: Hill, M.A. (2024, June 1) Embryology Jacob's syndrome. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Jacob%27s_syndrome

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G