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Introduction

Lymphatic system

While the structure of the lymphatic system (lympha = clear water) is well described, there is much to still learn about the complex development and function of this "system".

Immune - “monitor” of body surfaces, internal fluids
Extracellular fluid - returns interstitial fluid to circulation
Gastrointestinal tract - carries fat and fat-soluble vitamins

Aim

This lecture will provide an overview of the histology of key lymphoid organs, including the lymph nodes, spleen and thymus, as well as extranodal lymphoid tissues including mucosal associated lymphoid tissues (MALT)

Key Concepts

Lymphatic System
Organs - Thymus, Spleen
Lymph Nodes and Nodules
Bone Marrow
Extranodal Lymphoid Tissues
Mucosal Associated Lymphoid Tissues (MALT)

Textbook References

SH Laboratory Support
Janeway’s Immunobiology (see in additional information) NCBI Bookshelf
Histology and Cell Biology - A.L. Kiersenbaum (2001) Chapter 6: Blood, Chapter 10: Immune-Lymphatic
Previous Lectures: 2012 | 2010 | 2008

Historic Embryology
1909 Lymph glands \| 1912 Development of the Lymphatic System \| 1918 Gray's Lymphatic Images \| 1916 Pig Lymphatics \| 1919 Chicken Lymphatic \| 1921 Spleen \| 1922 Pig Stomach Lymphatics \| 1932 Cat Pharyngeal Tonsil \| Historic Disclaimer

Tonsil
Tonsil and MALT
Thymus
Spleen
Bone marrow