File:Spleen structure 02.jpg: Difference between revisions

Revision as of 19:01, 22 February 2012

Spleen Structure Cartoon

White pulp - consists of T cell zones (also known as the periarteriolar lymphoid sheath (PALS)) containing networks of fibroblastic reticular cells (FRC) surrounding a central arteriole, together with B cell follicles containing a central network of follicular dendritic cells (FDC).
- Immune cells enter the white pulp at regions where the T cell zones abut the MZ, known as the MZ bridging channels.
Marginal zones - (MZ) surrounding the white pulp contain marginal reticular cells (MRC), particularly at the edges of the B cell follicles.
Central arteriole - Blood and leukocytes entering the spleen pass through branches of the central arteriole, which end in the marginal sinuses and red pulp.
Red pulp - In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining.
- Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown).

Reference

<pubmed>19644499</pubmed>| PMC2785037 | Nat Rev Immunol.

Mueller

Permissions

File history

Click on a date/time to view the file as it appeared at that time.

	Date/Time	Thumbnail	Dimensions	User	Comment
current	18:55, 22 February 2012		401 × 463 (46 KB)	Z8600021 (talk \| contribs)

You cannot overwrite this file.

File usage

The following 4 pages use this file:

@@ Line 1: / Line 1: @@
 ==Spleen Structure Cartoon==
-Schematic representation of the organization of the spleen (left panel).
+* '''White pulp''' - consists of T cell zones (also known as the periarteriolar lymphoid sheath (PALS)) containing networks of fibroblastic reticular cells (FRC) surrounding a central arteriole, together with B cell follicles containing a central network of follicular dendritic cells (FDC).
+** Immune cells enter the white pulp at regions where the T cell zones abut the MZ, known as the MZ bridging channels.
-* The white pulp consists of T cell zones (also known as the periarteriolar lymphoid sheath (PALS)) containing networks of fibroblastic reticular cells (FRC) surrounding a central arteriole, together with B cell follicles containing a central network of follicular dendritic cells (FDC).
+* '''Marginal zones''' - (MZ) surrounding the white pulp contain marginal reticular cells (MRC), particularly at the edges of the B cell follicles.
-* Marginal zones (MZ) surrounding the white pulp contain marginal reticular cells (MRC), particularly at the edges of the B cell follicles.
+* '''Central arteriole''' - Blood and leukocytes entering the spleen pass through branches of the central arteriole, which end in the marginal sinuses and red pulp.
-* Blood and leukocytes entering the spleen pass through branches of the central arteriole, which end in the marginal sinuses and red pulp.
+* '''Red pulp''' - In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining.
-* In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining.
+** Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown).
-* Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown).
-* Immune cells enter the white pulp at regions where the T cell zones abut the MZ, known as the MZ bridging channels.
 ===Reference===