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(==Mouse Pancreas Development== Remodeling of the pancreatic epithelial cell mass into polarized monolayers. Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and la) |
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Remodeling of the pancreatic epithelial cell mass into polarized monolayers. | Remodeling of the pancreatic epithelial cell mass into polarized monolayers. | ||
Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and laminin. Pancreatic development starts by the formation of a mass of non-polarized epithelial cells (e10.5-e11.5). This mass is then remodeled (e12.5-e13.5) and finally every epithelial cell become polarized, with its basal pole contacting laminin and its apical pole facing a lumen (e14.5-e15.5). <nowiki>*</nowiki> indicates the central duct, in connection with the duodenum. | * Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and laminin. | ||
* Pancreatic development starts by the formation of a mass of non-polarized epithelial cells (e10.5-e11.5). | |||
* This mass is then remodeled (e12.5-e13.5) and finally every epithelial cell become polarized, with its basal pole contacting laminin and its apical pole facing a lumen (e14.5-e15.5). | |||
:<nowiki>*</nowiki> indicates the central duct, in connection with the duodenum. | |||
Scale bar, 100 μm. | Scale bar, 100 μm. | ||
| Line 17: | Line 21: | ||
© 2009 Hick et al; licensee BioMed Central Ltd. | © 2009 Hick et al; licensee BioMed Central Ltd. | ||
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | ||
[[Category:Mouse]] [[Category:Pancreas]] [[Category:Mouse]] [[Category:Fluorescence]] | |||
Revision as of 19:10, 9 July 2011
Mouse Pancreas Development
Remodeling of the pancreatic epithelial cell mass into polarized monolayers.
- Pancreatic sections from e10.5 to e15.5 embryos were examined by immunofluorescence using antibodies directed against E-cadherin, mucin-1 and laminin.
- Pancreatic development starts by the formation of a mass of non-polarized epithelial cells (e10.5-e11.5).
- This mass is then remodeled (e12.5-e13.5) and finally every epithelial cell become polarized, with its basal pole contacting laminin and its apical pole facing a lumen (e14.5-e15.5).
- * indicates the central duct, in connection with the duodenum.
Scale bar, 100 μm.
Original file name: 1471-213X-9-66-1.jpg
Reference
<pubmed>20003423</pubmed>| BMC Dev Biol.
Hick et al. BMC Developmental Biology 2009 9:66 doi:10.1186/1471-213X-9-66
© 2009 Hick et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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