2014 Group Project 6: Difference between revisions
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<pubmed>10.1371/journal.pone.0016752</pubmed> | <pubmed>10.1371/journal.pone.0016752</pubmed> | ||
===Thyroid Development=== | |||
The functional unit of the thyroid gland is the follicle hence it is necessary to understand how the follicle develops in order to understand the important function of this gland. There are progenitor cells in the anterior endoderm that are specified thyroid progenitor cells and contribute to thyroid organogenesis. The proliferation of these cells results in the formation of a placode along the midline of the pharyngeal floor, just below the future tongue. The left and right lobes of the thyroid gland start off as single structures: buds of endoderm surrounded by mesoderm. | |||
The mammalian thyroid gland is unique in the sense that there is a second endocrine cell called the parafollicular C cell. The progenitor cell for this enters the gland at the stage where there is a fusion between the thyroid progenitor proper and the ultimobranchial bodies. The ultimobranchial bodies arise bilaterally in the most inferior pharyngeal arches and are important in the final organ. | |||
Eventually the midline primordium stretches laterally to reach the ultimobranchial bodies and there is a bilobation event resulting in the recognisable bilobed thyroid gland. | |||
<pubmed>24290349</pubmed> | |||
==Parathyroid gland== | ==Parathyroid gland== | ||
Revision as of 21:24, 2 September 2014
| 2014 Student Projects | ||||
|---|---|---|---|---|
| 2014 Student Projects: Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8 | ||||
| The Group assessment for 2014 will be an online project on Fetal Development of a specific System.
This page is an undergraduate science embryology student and may contain inaccuracies in either description or acknowledgements. | ||||
The Endocrine System
--Mark Hill (talk) 15:18, 26 August 2014 (EST) OK you have 2 sub-headings after 2 weeks work, and I even had to add the title for your project. How about some content, references, sources for each section. See Lab 3 Assessment.
Introduction
--Z3414648 (talk) 15:23, 26 August 2014 (EST)
Pineal gland
<pubmed>9852259</pubmed>
M. Hulsemann, 1971, Development of the Innervation in the Human Pineal Organ, Light and Electron Microscopic Investigations, 115: 396-415
<pubmed>16021838</pubmed>
Hypothalamus
<pubmed>11954031</pubmed>
<pubmed>7643957</pubmed>
Y. Koutcherov, J.K, Mai, G. Paxinos Hypothalamus of the human fetus, Journal of Chemical Neuroanatomy, 26:4, pp 253–270
Pituitary gland
<pubmed>10.1016/j.acthis.2014.04.003</pubmed>
<pubmed>10.1371/journal.pone.0004815</pubmed>
<pubmed>10.1371/journal.pone.0004513</pubmed>
Thyroid
<pubmed>10.1371/journal.pone.0080801</pubmed>
<pubmed>10.1530/JOE-14-0025</pubmed>
<pubmed>10.1371/journal.pone.0016752</pubmed>
Thyroid Development
The functional unit of the thyroid gland is the follicle hence it is necessary to understand how the follicle develops in order to understand the important function of this gland. There are progenitor cells in the anterior endoderm that are specified thyroid progenitor cells and contribute to thyroid organogenesis. The proliferation of these cells results in the formation of a placode along the midline of the pharyngeal floor, just below the future tongue. The left and right lobes of the thyroid gland start off as single structures: buds of endoderm surrounded by mesoderm.
The mammalian thyroid gland is unique in the sense that there is a second endocrine cell called the parafollicular C cell. The progenitor cell for this enters the gland at the stage where there is a fusion between the thyroid progenitor proper and the ultimobranchial bodies. The ultimobranchial bodies arise bilaterally in the most inferior pharyngeal arches and are important in the final organ.
Eventually the midline primordium stretches laterally to reach the ultimobranchial bodies and there is a bilobation event resulting in the recognisable bilobed thyroid gland.
<pubmed>24290349</pubmed>
Parathyroid gland
<pubmed>22808183</pubmed> <pubmed>22649358</pubmed> <pubmed>21881196</pubmed> <pubmed>21904825</pubmed>
Thymus
<pubmed>21733645</pubmed> <pubmed>20836742</pubmed> <pubmed>21263742</pubmed> <pubmed>512270</pubmed>
Pancreas
<pubmed>22761699</pubmed> <pubmed>22893718</pubmed> <pubmed>24496309</pubmed> <pubmed>24595965</pubmed> <pubmed>23822675</pubmed> <pubmed>22968764</pubmed>
Adrenal gland
<pubmed>7011178</pubmed>
<pubmed>24116052</pubmed>
Gonad development
<pubmed>17237341</pubmed>
<pubmed>7623307</pubmed>
Placenta
<pubmed>10419690</pubmed>
<pubmed>7673080</pubmed>
Timeline
Associated Abnormalities
<pubmed>22808198</pubmed>
