File:Molecular endocrine pancreas cells 01.jpg: Difference between revisions
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* '''Arx''' - Aristaless-Related Homeobox, X-Linked [http://www.omim.org/entry/300382 OMIM 300382] | * '''Arx''' - Aristaless-Related Homeobox, X-Linked [http://www.omim.org/entry/300382 OMIM 300382] | ||
** homeobox protein that belongs to the Aristaless-related subset of the paired (Prd) class of homeodomain proteins. | |||
* '''Nkx2.2''' - NK2 Homeobox 2 [http://omim.org/entry/604612 OMIM 604612] | * '''Nkx2.2''' - NK2 Homeobox 2 [http://omim.org/entry/604612 OMIM 604612] | ||
** homeobox (Hox) containing transcription factor contain a 60-amino acid evolutionarily conserved DNA-binding homeodomain. | ** homeobox (Hox) containing transcription factor contain a 60-amino acid evolutionarily conserved DNA-binding homeodomain. | ||
* '''Pax4''' - Paired Box Gene 4 [http://omim.org/entry/167413 OMIM 167413] | * '''Pax4''' - Paired Box Gene 4 [http://omim.org/entry/167413 OMIM 167413] | ||
** transcription factor containing a paired box domain. | ** transcription factor containing a paired box domain. |
Revision as of 08:52, 31 August 2014
Molecular Development of Endocrine Pancreas Cells
Model placing gastrin cells in the transcriptional hierarchy of endocrine cells in the pancreas.
Pancreatic G cells
- similar to alpha cells in that it is dependent on Arx.
- similar to epsilon cells in that both gastrin and ghrelin are frequently co-expressed with glucagon in the embryonic pancreas.
- Links: Endocrine ancreas | Pax | Molecular Development
Factor Information | |
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References
<pubmed>23940571</pubmed>| PLoS One.
Copyright
© 2013 Suissa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal.pone.0070397.g007.jpg
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