Template:Main Page News: Difference between revisions

Revision as of 13:00, 3 March 2014

News - DNA sequencing versus standard prenatal aneuploidy screening

Stimulus-triggered acquisition of pluripotency 01.jpg

"In high-risk pregnant women, noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-free DNA (cfDNA testing) accurately detects fetal autosomal aneuploidy. Its performance in low-risk women is unclear. ...In a general obstetrical population, prenatal testing with the use of cfDNA had significantly lower false positive rates and higher positive predictive values for detection of trisomies 21 and 18 than standard screening. (Funded by Illumina; ClinicalTrials.gov number, NCT01663350.)." (More? Trisomy_21 | Trisomy_18 | Prenatal Diagnosis)

<pubmed>24571752</pubmed>| N Engl J Med.

@@ Line 1: / Line 1: @@
 {|
 |-bgcolor="CEDFF2"
-| colspan=2|<span style="font-size:150%">'''News - Stimulus-triggered fate conversion of somatic cells into pluripotency'''</span>
+| colspan=2|<span style="font-size:150%">'''News - DNA sequencing versus standard prenatal aneuploidy screening'''</span>
 |-bgcolor="F5FAFF"
 | <center>[[File:Stimulus-triggered acquisition of pluripotency 01.jpg]]</center>
 |-bgcolor="F5FAFF"
 |
-:"Here we report a unique cellular reprogramming phenomenon, called stimulus-triggered acquisition of pluripotency (STAP), which requires neither nuclear transfer nor the introduction of transcription factors. In STAP, strong external stimuli such as a transient low-pH stressor reprogrammed mammalian somatic cells, resulting in the generation of pluripotent cells." (More? [http://www.nature.com/nature/journal/v505/n7485/full/nature12968.html Nature paper] | [[Stem_Cells_-_Induced|Induced Stem Cells]] | [[Stem Cells]])
+[[File:Chromosome- trisomy.jpg|250px|left]]
-|}<noinclude>[[Category:Template]][[Category:2014]]</noinclude>
+: "In high-risk pregnant women, noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-free DNA (cfDNA testing) accurately detects fetal autosomal aneuploidy. Its performance in low-risk women is unclear. ...In a general obstetrical population, prenatal testing with the use of cfDNA had significantly lower false positive rates and higher positive predictive values for detection of trisomies 21 and 18 than standard screening. (Funded by Illumina; ClinicalTrials.gov number, NCT01663350.)." (More? [[Trisomy_21]] |  [[Trisomy_18]] | [[Prenatal Diagnosis]])
-'''Is STAP Real?'''
+<pubmed>24571752</pubmed>| [http://www.nejm.org/doi/full/10.1056/NEJMoa1311037 N Engl J Med.]
-Japanese research institute has opened an investigation into this groundbreaking stem cell study after concerns were raised about its credibility. The RIKEN investigation follows allegations on blog sites about the use of duplicated images in Obokata’s papers, and numerous failed attempts to replicate her results.  [http://www.nature.com/news/acid-bath-stem-cell-study-under-investigation-1.14738 Nature]
+|}<noinclude>[[Category:Template]][[Category:2014]]</noinclude>