File:Aschheim-Zondek Test 1928.gif: Difference between revisions
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:'''Links:''' [[Pregnancy Test]] | [[Menstrual Cycle]] | [[Week 2]] | :'''Links:''' [[Pregnancy Test]] | [[Menstrual Cycle]] | [[Week 2]] | [[Mouse Development]] | [[Frog Development]] | ||
Revision as of 11:07, 15 November 2012
Aschheim-Zondek Test (1928)
The basis of the original historic Aschheim-Zondek[1] test developed in 1928 was to identify the changes in immature female mouse genital system by female human urine injected subcutaneously into these immature mice.
- If the woman was pregnant - the presence of hormones (hCG) induced changes in the mouse genital tract physiologically similar to those produced by sex hormones.
- follicle maturation, corpora heamorrhagicum and corpora lutea formation.
- If the woman was not pregnant - there were no changes induced.
This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus frog.
Animation based upon original line drawings.[2]
- Links: Pregnancy Test | Menstrual Cycle | Week 2 | Mouse Development | Frog Development
Reference
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