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Human Spermatozoa Phospholipase C zeta Localization

Developmental localization of PLCζ in human (B, C) testes utilizing anti-hmPLCζ antibody. In human, there are six stages (I–VI) of the cycle of the seminiferous epithelium.

B - (stage II) PLCζ accumulates over the acrosomic vesicle (AV) of step 2 spermatids. Little immunoreactivity is found elsewhere in the epithelium and the elongated spermatids (arrowheads) appear unreactive.
C - (stage IV) step 4 spermatids the fully formed acrosome is intensely labeled (arrows).

Bars = 20 µm

Reference

<pubmed>22428063</pubmed>| PLoS One.

Citation: Aarabi M, Yu Y, Xu W, Tse MY, Pang SC, et al. (2012) The Testicular and Epididymal Expression Profile of PLCζ in Mouse and Human Does Not Support Its Role as a Sperm-Borne Oocyte Activating Factor. PLoS ONE 7(3): e33496. doi:10.1371/journal.pone.0033496

Copyright: © 2012 Aarabi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Journal.pone.0033496.g002.jpg

Panel B and C from Figure 2. Developmental localization of PLCζ in mouse (A) and human (B, C) testes utilizing anti-hmPLCζ antibody.

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current	12:55, 6 May 2012		1,000 × 571 (119 KB)	Z8600021 (talk \| contribs)	Human Spermatozoa Phospholipase C zeta Localization== Figure 2. Developmental localization of PLCζ in mouse (A) and human (B, C) testes utilizing anti-hmPLCζ antibody. Similar results were obtained with anti-EF antibody in mouse and human and anti-hPLC

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Spermatozoa Development

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	Panel B and C from Figure 2. Developmental localization of PLCζ in mouse (A) and human (B, C) testes utilizing anti-hmPLCζ antibody.		Panel B and C from Figure 2. Developmental localization of PLCζ in mouse (A) and human (B, C) testes utilizing anti-hmPLCζ antibody.

			[[Category:Human]] [[Category:Spermatozoa]]