Talk:BGDB Gastrointestinal - Activity 4: Difference between revisions
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Gastrointestinal malformations, associated congenital abnormalities, and intrauterine growth | ===Gastrointestinal malformations, associated congenital abnormalities, and intrauterine growth=== | ||
{{#pmid:11930098}} | {{#pmid:11930098}} | ||
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CONCLUSIONS: | CONCLUSIONS: | ||
Gastrointestinal malformations often are complicated by skeletal anomalies and intrauterine growth retardation. The association among these disorders requires further investigation. However, from a practical point of view, this association should be considered in treating affected patients. | Gastrointestinal malformations often are complicated by skeletal anomalies and intrauterine growth retardation. The association among these disorders requires further investigation. However, from a practical point of view, this association should be considered in treating affected patients. | ||
===Malformations, choristomas, and hamartomas of the gastrointestinal tract and pancreas=== | |||
{{#pmid:30482417}} | |||
Johncilla M1, Yantiss RK1. | |||
Author information | |||
Abstract | |||
Congenital and hamartomatous lesions of the gastrointestinal tract cause diagnostic challenges for surgical pathologists. Many of these are merely histologic curiosities, whereas others have substantial clinical implications because they herald cancer syndromes or associated anomalies. Although a comprehensive discussion of all developmental abnormalities that can occur in the gastrointestinal tract is beyond the scope of a single manuscript, some entities are more likely to be encountered by surgical pathologists, have important clinical consequences, or pose diagnostic difficulties. The purpose of this review is to discuss the more common malformations and choristomas, as well as hamartomatous lesions that may be clinically important due to their risk for cancer development, frequent associations with heritable cancer syndromes and other anomalies, or potential to simulate other entities. | |||
Copyright © 2018. Published by Elsevier Inc. | |||
PMID: 30482417 DOI: 10.1053/j.semdp.2018.11.004 | |||
Revision as of 09:55, 24 January 2019
1. Fetal and Postnatal Changes
2. Common Abnormalities
What is the most common gastrointestinal abnormality of the newborn?
Gastrointestinal malformations, associated congenital abnormalities, and intrauterine growth
Tárnok A & Méhes K. (2002). Gastrointestinal malformations, associated congenital abnormalities, and intrauterine growth. J. Pediatr. Gastroenterol. Nutr. , 34, 406-9. PMID: 11930098
Tárnok A1, Méhes K.
Abstract BACKGROUND: In contrast with other malformations, congenital anomalies of the gastrointestinal tract have been scarcely investigated. METHODS: The prevalence of gastrointestinal malformations with special reference to associated disorders and intrauterine growth was retrospectively analyzed in the newborn infants admitted to the Neonatal Intensive Care Unit of the Department of Pediatrics, University of Pécs, Hungary, in the 14-year period between 1987 and 2000. RESULTS: Of 4,241 neonates with gastrointestinal malformations, 241 (5.68%) had a total of 304 malformations (excluding Hirschsprung disease). In 133 patients, the gastrointestinal anomalies were observed as one of multiple malformations; a specific syndrome or association was diagnosed in 36 cases. Skeletal disorders were the most frequently associated anomalies. Intrauterine growth retardation was found in a large number of patients with both isolated and multiple gastrointestinal malformations (38.9% and 30.8%, respectively). CONCLUSIONS: Gastrointestinal malformations often are complicated by skeletal anomalies and intrauterine growth retardation. The association among these disorders requires further investigation. However, from a practical point of view, this association should be considered in treating affected patients.
Malformations, choristomas, and hamartomas of the gastrointestinal tract and pancreas
Johncilla M & Yantiss RK. (2018). Malformations, choristomas, and hamartomas of the gastrointestinal tract and pancreas. Semin Diagn Pathol , , . PMID: 30482417 DOI.
Johncilla M1, Yantiss RK1. Author information Abstract Congenital and hamartomatous lesions of the gastrointestinal tract cause diagnostic challenges for surgical pathologists. Many of these are merely histologic curiosities, whereas others have substantial clinical implications because they herald cancer syndromes or associated anomalies. Although a comprehensive discussion of all developmental abnormalities that can occur in the gastrointestinal tract is beyond the scope of a single manuscript, some entities are more likely to be encountered by surgical pathologists, have important clinical consequences, or pose diagnostic difficulties. The purpose of this review is to discuss the more common malformations and choristomas, as well as hamartomatous lesions that may be clinically important due to their risk for cancer development, frequent associations with heritable cancer syndromes and other anomalies, or potential to simulate other entities. Copyright © 2018. Published by Elsevier Inc. PMID: 30482417 DOI: 10.1053/j.semdp.2018.11.004
Gastrointestinal disorders can affect neonates and infants:
Gastroesophageal reflux
Hypertrophic pyloric stenosis
Intussusception
Meconium ileus
Meconium plug syndrome
Necrotizing enterocolitis
Neonatal cholestasis
