File:Spleen structure 02.jpg: Difference between revisions
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* '''Red pulp''' - In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining. | * '''Red pulp''' - In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining. | ||
** Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown). | ** Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown). | ||
{{Spleen Histology}} | |||
===Reference=== | ===Reference=== | ||
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[[File_talk:Spleen_structure_02.jpg|Permissions]] | [[File_talk:Spleen_structure_02.jpg|Permissions]] | ||
[[Category:Spleen]] [[Category:Cartoon]] | |||
Latest revision as of 12:51, 26 February 2012
Spleen Structure Cartoon
- White pulp - consists of T cell zones (also known as the periarteriolar lymphoid sheath (PALS)) containing networks of fibroblastic reticular cells (FRC) surrounding a central arteriole, together with B cell follicles containing a central network of follicular dendritic cells (FDC).
- Immune cells enter the white pulp at regions where the T cell zones abut the MZ, known as the MZ bridging channels.
- Marginal zones - (MZ) surrounding the white pulp contain marginal reticular cells (MRC), particularly at the edges of the B cell follicles.
- Central arteriole - Blood and leukocytes entering the spleen pass through branches of the central arteriole, which end in the marginal sinuses and red pulp.
- Red pulp - In the cords of the red pulp, a dense network of reticular fibroblasts and fibres construct an open blood network, which is marked by its lack of a typical endothelial cell lining.
- Large numbers of macrophages phagocytose dying or damaged red blood cells in the red pulp (not shown).
Reference
<pubmed>19644499</pubmed>| PMC2785037 | Nat Rev Immunol.
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