File:FGF signalling pathway.jpg: Difference between revisions
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Latest revision as of 09:58, 31 August 2017
FGF Signalling Pathway
Description
Summary of the FGFR signalling pathway. The FGFR signalling pathway is capable of altering DNA expression through the downstream signalling of PI3K, RAS and IP3 pathways. This will stimulate the binding of Elk1 and ATF2 directly to DNA within the nucleus of cells therefore altering gene expression. Abbreviations: ATF2 (Activating transcription factor 2), Ca2+(calcium ions), CDC42(Cell division control protein 42 homolog), DAG(diacylglycerol), Elk1( ETS-DOMAIN PROTEIN 1), ERK1/2(Extracellular Signal-Regulated Kinases 1 and 2), FRS2(Fibroblast growth factor receptor substrate 2), GAP(GTPase-Activating Proteins), GDP ( guanosine diphosphate), GRB2(Growth factor receptor-bound protein 2 ), GTP(guanosine triphosphate), IP3(Inositol trisphosphate or inositol 1,4,5-trisphosphate), JNK(c-Jun N-terminal kinases), MEKK(MAPK/Erk kinase kinase), MKK3/6(Dual specificity mitogen-activated protein kinase 3 and 6), RA1 (Retinoic acid 1), Rac1 (Ras-Related C3 Botulinum Toxin Substrate 1), PLC(Phospholipase C), PLD(Phospholipase D), SOS(Son of Sevenless)
References
Image was drawn from the signalling pathway presented in: [1]
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- ↑ <pubmed>27458533</pubmed>
File history
Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan
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current | 14:52, 28 September 2016 | 3,507 × 2,550 (1.11 MB) | Z5015544 (talk | contribs) | <b> Summary of the FGFR signalling pathway.</b> The FGFR signalling pathway is capable of altering DNA expression through the downstream signalling of PI3K, RAS and IP3 pathways. This will stimulate the binding of Elk1 and ATF2 directly to DNA within t... |
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