File:MLPA of TDR.jpeg: Difference between revisions

This image shows a detailed map of the distal typically deleted region (TDR) in chromosome 22q11.2. The MLPA probes are shown in blue font, with STR (Short Tandem Repeats) shown in black and SNP (single nucleotide polymorphisms) in grey font. This detailed map is hence a compilation of information obtained using a variety of imaging techniques (not just MLPA). The advent of these technologies has greatly enhanced our ability to visualise and decoded this particular chromosome and the disorders associated.

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A deletion and a duplication in distal 22q11.2 deletion syndrome region. Clinical implications and review Luis Fernández, Julián Nevado, Fernando Santos, Damià Heine-Suñer, Victor Martinez-Glez, Sixto García-Miñaur, Rebeca Palomo, Alicia Delicado, Isidora López Pajares, María Palomares, Luis García-Guereta, Eva Valverde, Federico Hawkins, Pablo Lapunzina BMC Med Genet. 2009; 10: 48. Published online 2009 June 2. doi: 10.1186/1471-2350-10-48 PMCID: PMC2700091

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