File:Model Hox10 kidney development.jpg: Difference between revisions

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Model Hox10 Kidney Development

Model depicting the role of the Hox10 genes in the proper differentiation and integration of the cortical stromal cells during mammalian kidney development.

Transcription factors and signals for ureteric bud induction: Hox11, Pax2, Eya1, Wt1, and Sall1 promote Gdnf expression in the condensed metanephric mesenchyme prior to ureteric bud induction.^[1]

Links: Hox | Renal System Development

Original File name: Figure 9. Journal.pone.0023410.g009.jpg

Reference

Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM (2011) Hox10 Genes Function in Kidney Development in the Differentiation and Integration of the Cortical Stroma. PLoS ONE 6(8): e23410. PMID 21858105 PloS One

↑ PMID 21553325

© 2011 Yallowitz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current	12:44, 2 September 2011		600 × 627 (36 KB)	S8600021 (talk \| contribs)	==Model Hox10 Kidney Development== Model depicting the role of the Hox10 genes in the proper differentiation and integration of the cortical stromal cells during mammalian kidney development. Figure 9. Journal.pone.0023410.g009.jpg ===Reference=== Yal

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Developmental Signals - Homeobox

[1] PMID 21553325

[1]

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-Transcription factors and signals necessary for ureteric bud induction.<ref>PMID 21553325</ref>
+Transcription factors and signals for ureteric bud induction: Hox11, Pax2, Eya1, Wt1, and Sall1 promote Gdnf expression in the condensed metanephric mesenchyme prior to ureteric bud induction.<ref>PMID 21553325</ref>
-* Hox11, Pax2, Eya1, Wt1, and Sall1 - promote Gdnf expression in the condensed metanephric mesenchyme prior to ureteric bud induction.
-* Foxc1, Foxc2, Robo, and Slit - limit the anteroposterior (AP) expression boundary of Gdnf in the mesenchyme.
-* Gdnf - recognized by cRet and Gfrα1 receptors on the ureteric bud, which forms from the Wolffian duct.
+:'''Links:''' [[Developmental_Signals_-_Homeobox|Hox]] | [[Renal System Development]]
-:Links:
 Original File name: Figure 9. Journal.pone.0023410.g009.jpg