File:Mouse E14.5 gene expression.jpg: Difference between revisions

Mouse (E14.5) Representative examples of RNA ISH data

The expression categories defined by the annotation summary are illustrated by the following examples.

1. Expression not detected: Rassf1 messenger RNA is not detected at this stage.
2. Homogeneous (non-regional) signal: Wdr68 shows hybridization signal in all tissues and structures.
3. Regionally expressed genes: Crmp1, Mir124, Titf1, and 1300010A20Rik.

• Crmp1 signal is evident in the brain, the V trigeminal ganglion, the spinal cord, and the neural retina.
• miR124 is restricted to the nervous system.
• Titf1 expression is detected in the diencephalon, hypothalamus, telencephalon, thyroid, and lung.
• 1300010A20Rik is an example of a tissue-specific gene with expression limited to the liver.

Complete sets of images for 19,411 genes are available at http://www.eurexpress.org.

Links: Mouse E14.5 gene expression | Titf1 expression | Mouse Development | Eurexpress transcriptome atlas

Original file name: Figure 1. Journal.pbio.1000582.g001.jpg http://www.plosbiology.org/article/slideshow.action?uri=info:doi/10.1371/journal.pbio.1000582&imageURI=info:doi/10.1371/journal.pbio.1000582.g001

Reference

<pubmed>21267068</pubmed>| PLoS Biol. | Eurexpress transcriptome atlas

Citation: Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, et al. (2011) A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo. PLoS Biol 9(1): e1000582. doi:10.1371/journal.pbio.1000582

Copyright: © 2010 Diez-Roux et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.