Template:BGDB Sexual Differentiation - Abnormalities Interactive

Abnormalities Interactive Component

Attempt the Quiz - Abnormalities

Here are a few simple Quiz questions that relate to Abnormalities of genital development from the lecture and practical. 1 In a genetic male (44 x XY) who lacks androgen receptors, each of the following will be increased except:   estradiol   FSH   LH   progesterone   testosterone 2 The best option below for a child born with ambiguous external genitalia could be:   46,XX DSD a female pseudohermaphrodite   46,XY DSD a male pseudohermaphrodite   Ovotesticular DSD   someone with Klinefelter’s syndrome   any of the above 3 In monosomy XO (Turner’s syndrome):   the children start normal male development   the number of germ cells in the gonads starts decreasing after puberty   the children grow disproportionately tall   an active gene on a dormant X chromosome may account for the clinical manifestations   all of the above might occur 4 If 46,XY DSD is due to androgen receptor disorders, then:   the testes are normal for the most part   the testosterone and DHT levels are normal   MDIF is secreted by the Sertoli cells   the fetus will have female external genitalia without a female genital tract   all of the above is correct 5 Failure of formation and migration of the primordial germ cells results in:   Turner’s syndrome   Klinefelter’s syndrome   46,XX DSD   gonadal agenesis   none of the above 6 Failure of the urethral folds to fuse prenatally would be expected to result in:   epispadias   exstrophy of urinary bladder   horseshoe kidney   hypospadias   multiple ureters Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio Additional Information: genital abnormalities