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| ====Copyright==== | | ====Copyright==== |
| | © 2008 Annals of Pediatric Cardiology |
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| Prevalence of congenital anomalies in newborns with congenital heart disease diagnosis.
| | The entire contents of the Annals of Pediatric Cardiology are protected under Indian and international copyrights. The Journal, however, grants to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, perform and display the work publicly and to make and distribute derivative works in any digital medium for any reasonable non-commercial purpose, subject to proper attribution of authorship and ownership of the rights. |
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| Ann Pediatr Cardiol. 2014 May;7(2):86-91. doi: 10.4103/0974-2069.132474.
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| Egbe A1, Lee S1, Ho D2, Uppu S1, Srivastava S1.
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| Abstract
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| BACKGROUND:
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| There is a known association between congenital heart disease (CHD) and other congenital anomalies (CA). These associations have been altered by changes in prenatal factors in recent time. We reviewed the largest database of inpatient hospitalization information and analyzed the current association between common CHD diagnoses and other congenital anomalies.
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| MATERIALS AND METHODS:
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| Case-control study design. We reviewed the Nationwide Inpatient Sample (NIS) database from 1998 to 2008 and identified all live births with CHD diagnosis (case) and live births without CHD diagnosis (control). We compared prevalence of associated congenital anomalies between the case and control groups.
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| RESULTS:
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| Our cohort consisted of 97,154 and 12,078,482 subjects in the case and control groups, respectively. In the CHD population, prevalence of non-syndromic congenital anomaly (NSCA), genetic syndrome (GS), and overall extra-cardiac congenital anomaly (CA) were 11.4, 2.2, and 13.6%, respectively. In the control group, prevalence of NSCA, GS, and CA were 6.7, 0.3, and 7.0%, respectively. NSCA (odds ratio (OR): 1.88, confidence interval (CI): 1.73-1.94), GS (OR 2.52, CI 2.44-2.61), and overall CA (OR: 2.01, CI: 1.97-2.14) were strongly associated with CHD. Prevalence of GS and multiple organ-system CA decreased significantly over the study period.
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| CONCLUSIONS:
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| This is the largest and most comprehensive population-based study evaluating association between CHD and extra-cardiac malformation (ECM) in newborns. There was significant decrease in prevalence of GS and multiple CA over the study period.
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| KEYWORDS:
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| Congenital anomalies; epidemiology; extra cardiac; newborn; prevalence
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| PMID 24987252
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Revision as of 17:17, 21 February 2015
Nationwide Inpatient Sample (NIS) database from 1998 to 2008
Reference
<pubmed>24987252</pubmed>| Ann Pediatr Cardiol.
Copyright
© 2008 Annals of Pediatric Cardiology
The entire contents of the Annals of Pediatric Cardiology are protected under Indian and international copyrights. The Journal, however, grants to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, perform and display the work publicly and to make and distribute derivative works in any digital medium for any reasonable non-commercial purpose, subject to proper attribution of authorship and ownership of the rights.
Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan
| Gwalagizhi | Nyangagi | Dimensions | User | Comment |
current | 17:13, 21 February 2015 | ![Thumbnail for version as of 17:13, 21 February 2015](/embryology/images/thumb/f/ff/Non-syndrome_abnormalities_USA_1998-2008_graph.jpg/120px-Non-syndrome_abnormalities_USA_1998-2008_graph.jpg?20150221071305) | 770 × 502 (40 KB) | Z8600021 (talk | contribs) | Nationwide Inpatient Sample (NIS) database from 1998 to 2008 ===Reference=== <pubmed>24987252 </pubmed> ====Copyright==== Prevalence of congenital anomalies in newborns with congenital heart disease diagnosis. Ann Pediatr Cardiol. 2014 May;7(2):86... |
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