Testis Descent Movie

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Beginning

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End

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Testis Descent

Data from a study of male human fetal (between 10 and 35 weeks) gonad position[1]

  • 10 to 23 weeks - (9.45%) had migrated from the abdomen and were situated in the inguinal canal
  • 24 to 26 weeks - (57.9%) had migrated from the abdomen
  • 27 to 29 weeks - (16.7%) had not descended to the scrotum


Gubernaculum

  • mesenchymal structure occurring associated with gonad development and involved in testes descent.
  • Two factors - insulin-like peptide hormone 3 (INSL3) and androgen, have been shown to be involved with gubernaculum development. Insulin-like peptide 3 (INSL3) hormone receptor is RXFP20.

Human gubernaculum development: 8-12 weeks - mesonephric fold at or near the gonad; 20-25 weeks - connected to the testis or uterus.[2]

References

  1. Sampaio FJ & Favorito LA. (1998). Analysis of testicular migration during the fetal period in humans. J. Urol. , 159, 540-2. PMID: 9649288
  2. Niikura H, Okamoto S, Nagase S, Takano T, Murakami G, Tatsumi H & Yaegashi N. (2008). Fetal development of the human gubernaculum with special reference to the fasciae and muscles around it. Clin Anat , 21, 547-57. PMID: 18661576 DOI.


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Cite this page: Hill, M.A. (2019, December 12) Embryology Testis Descent Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Testis_Descent_Movie

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G