Mouse Face Bmp4 Movie

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Mouse face Bmp4 icon.jpg

Animation showing the developmental expression of Bmp4 in the Mouse Face

Frontal views of the developing head of Bmp4lacZneo transgenic embryos. (Original images have been modified for this animation)

  • From E9.5 to E11.0, Bmp4 is expressed in the epithelium overlying the distal first branchial arch, maxillary and mandibular processes and medial and lateral nasal processes.
  • Expression in the ectoderm overlying the distal part of the first branchial arch at E9.5 and the mandibular process at E10.5.
  • At E12.5, endogenous Bmp4 expression shifts to the mesenchyme.
  • At E12.5 and 13.5, endogenous Bmp4 is concentrated in the mesenchyme of the midface including the whisker follicles.

Abbreviations: MxP, maxillary process; MdP, mandibular process; MNP, medial nasal process; LNP, lateral nasal process; NP, nasal pit; Mx, maxilla; Md, mandible.


BMP Mouse Links: Face and limb E9.5-13.5 | Face E9.5-13.5 | Body E11.0 | Body E11.5 | BMP | Mouse Development


Reference

Dolrudee Jumlongras, Salil A Lachke, Daniel J O'Connell, Anton Aboukhalil, Xiao Li, Sung E Choe, Joshua W K Ho, Annick Turbe-Doan, Erin A Robertson, Bjorn R Olsen, Martha L Bulyk, Brad A Amendt, Richard L Maas An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud. PLoS ONE: 2012, 7(6);e38568 PubMed 22701669

| PLoS One


Copyright

© 2012 Jumlongras et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation: Jumlongras D, Lachke SA, O’Connell DJ, Aboukhalil A, Li X, et al. (2012) An Evolutionarily Conserved Enhancer Regulates Bmp4 Expression in Developing Incisor and Limb Bud. PLoS ONE 7(6): e38568. doi:10.1371/journal.pone.0038568


doi:10.1371/journal.pone.0038568.g003 Figure 3. Journal.pone.0038568.g003.jpg Panels cropped and resized from full figure, above text modified from figure legend.


Cite this page: Hill, M.A. 2017 Embryology Mouse Face Bmp4 Movie. Retrieved October 22, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Mouse_Face_Bmp4_Movie

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© Dr Mark Hill 2017, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G