File:Newborn micrognathia 01.jpg

Newborn Micrognathia

Micrognathia is a clinical term for a facial malformation characterized by mandibular hypoplasia, generating a small receding chin that fails to maintain the tongue in a forward position. Several developmental causes including Pierre-Robin syndrome.

Links: Pierre Robin Syndrome | Head Development - Abnormalities

"At 34 weeks 5 days of gestation, a cesarean section was performed for non-reassuring fetal status. The female infant had a birth weight of 1,675 g, with an umbilical artery pH of 7.385. Apgar scores were 5 at one minute and 7 at five minutes. The infant had mandibular hypoplasia and glossoptosis and was diagnosed with Pierre Robin Syndrome (PRS). Severe respiratory compromise required immediate tracheostomy and cardiopulmonary resuscitation with mechanical ventilatory support. The infant's cardiopulmonary condition did not improve, and she died 21 hours after birth."

Reference

<pubmed>20716376</pubmed>| PMC2931455 | BMC Pregnancy Childbirth.

© 2010 Morokuma et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Panel C from Figure 1.

Figure 1. Fetal and newborn face. B-mode ultrasound scan of the fetal face at 33 weeks of gestation showing micrognathia (arrows: mandible) (a). Three-dimensional ultrasound scan of the fetal face at 33 weeks of gestation showing micrognathia (arrows: mandible) (b). Newborn face showing micrognathia (c).