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Expression Pattern of Fore-limb Specific Gene

Qualitatively some genes identified as forelimb or hindlimb specific do not appear to be restricted to one limb such as Sp6, SmarcD2 and Hoxc10, yet quantitatively these transcripts are >2 fold up-regulated in one limb in relationship to the other. Note original figure 8 does not give specific embryo age (range E9.5 - E13.5).


Limb Links: Mouse limb skeleton cartoon | Mouse limb tissue development | Limb Development | Mouse Development
Gene Expression Patterns: E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | Lmx1b | Forelimb | Tbx5 | Fbxo41 | Hoxc5 | Hoxb5 | Prdm1 | Hoxb6 | Etv2 | Egr1 | Figf | Sp6 | Cited1 | Prox1 | SmarcD2 | Echdc1 | Sim2 | Hindlimb | Tbx4 | Ptx1 | Hoxc10 | Hoxc9 | Dmrt2

Reference

Taher L, Collette NM, Murugesh D, Maxwell E, Ovcharenko I & Loots GG. (2011). Global gene expression analysis of murine limb development. PLoS ONE , 6, e28358. PMID: 22174793 DOI.

Copyright

This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

Figure 8. doi:10.1371/journal.pone.0028358.g008

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current15:55, 13 February 2013Thumbnail for version as of 15:55, 13 February 2013446 × 550 (37 KB)Z8600021 (talk | contribs)==Expression Pattern of Fore-limb Specific Gene== Qualitatively some genes identified as forelimb or hindlimb specific do not appear to be restricted to one limb such as Sp6, SmarcD2 and Hoxc10, yet quantitatively these transcripts are >2 fold up-regulate
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