From Embryology

1- What is the protein that the sperm binds to on the surface? zona pellucida lipoprotein ZP3 2-Name the three stages of follicle development? primordal follicle, pre-antral follicle and antral follicle(Graffian follicle is the mature follicle). --Angama Yaquobi 13:13, 6 August 2009 (EST)

Lab 2-

What factor do the synctiotrophoblast cells secrete to support the ongoing pregnancy? -Human Chorionic Gonadotrophin

What does the corpus luteum secrete to prevent continuation of the menstrual cycle? -estrogen and progesterone

What are the 2 main tissues to be derived from the germ cell layer continuous with the lining of the amniotic sac? - nervous system from the neural tube and neural crest -epithelial layer of the skin covering the embryo.

--Angama Yaquobi 13:06, 13 August 2009 (EST)

ASSESSMENT LAB 3 1. What period of human development (in weeks) do the 23 Carnegie stages cover? Weeks 8-9. 2. What part of the somite will contribute to the vertebral column? Sclerotome

--Angama Yaquobi 13:11, 20 August 2009 (EST)

3. At what Carnegie stage does the human neural tube normally completely close? Stage 13 --Angama Yaquobi 13:11, 20 August 2009 (EST)

  1.  Into what structure do most blood vessels empty before they enter the embryonic heart? 
  2. What do the dorsal aortas become in the adult? 


  3. What are the layers of cells found in a tertiary villi? 


--Angama Yaquobi 13:22, 27 August 2009 (EST)

Lab 5 Questions What was the question I said in the respiratory lecture would be part of this week's assessment? What is Congenital Diaphragmatic Hernia and how does it affect the human lungs?

Answer Congenital diaphragmatic hernia (CDH) is a term used to variety of congenital birth defects that involve abnormal development of the diaphragm which then can allow the abdominal contents to protrude into the chest thereby obstructing proper lung formation. Newborn with CDH often have severe respiratory distress which can be life threatening unless treated appropriately.

Lab 6 Questions

  1. Which is the more common clefting, cleft lip or cleft palate?
  2. What structures does pharyngeal pouch 1 form?
  3. Neural crest forms which cells within the skin? 

1- Cleft lip 2-Each pouch is lined with endoderm and has the following structures:tubotympanic recess,tympanic membrane, tympanic cavity, mastoid antrum, auditory tube. 3-Melanoblasts then differentiates into melanocytes. --Angama Yaquobi 14:09, 3 September 2009 (EST)

--Angama Yaquobi 14:39, 17 September 2009 (EST) What is a myotube and how is it formed? It is a multinucleated cell which is an undifferentiated contractile apparatus. It is formed by fusion of myoblasts which happens during skeletal development. What changes would I expect to see in the muscle fibre types in my legs if I: a) Suffered a spinal cord injury;

muscle atrophy as well as conversion of slow twitch muscle fibres to fast twitch muscle fibres. 

b) Took up marathon running;

muscle growth and conversion of fast twitch fibres to slow twitch fibres.


--Angama Yaquobi 13:33, 24 September 2009 (EST)

--Angama Yaquobi 13:07, 1 October 2009 (EST)

--Angama Yaquobi 14:22, 8 October 2009 (EST) Q 1. Identify and name 3 tissue types which contain adult (somatic) stem cells that were used/studied from the 5 articles discussed during the tutorial. Muscle, bone marrow, neural stem cells Q 2. Name 2 reprogramming strategies/methods used in generating human induced Pluripotent Stem Cells (iPSCs) from the 5 articles discussed during the tutorial. • Virus method. For instance, injecting the Gene using lentiviruses. • Non viral method. In this case, the plasmid is usually used. Q 3. Is the following statement TRUE or FALSE? "Unlike the nuclear genome, the mitochondrial DNA in the embryo is derived almost exclusively from the egg; that is, it is of maternal origin." True.

--Antonio Lee 15:15, 31 October 2009 (EST) 3/3 Correct.