User:Z3465654: Difference between revisions
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===Lab 1 Assessment=== | ===Lab 1 Assessment=== | ||
===Article 1=== | ====Article 1==== | ||
<pubmed>24760595</pubmed> | <pubmed>24760595</pubmed> | ||
The following case study investigated the effects of hepatitis B virus (HBV) infection on sperm parameters, ovarian stimulation, and outcomes of in vitro fertilization (IVF) and embryo transfer, as the impact of HBV on human infertility was questionable. During this study, a total of 224 couples were identified, where either one or both partners were HBsAg-seropositive, and were undergoing their first IVF and embryo transfer cycle. The morphology of their sperm was analysed, as was the quality of their embryo rate, the duration of infertility and their fertilization rates, and then compared to those of 448 HBsAg-seronegative couples. In all four cases, the results of the HBsAg-seropositive couples were inferior to those of the HBsAg-seronegative couples, expressing significantly lower normal sperm morphology, top-quality embryo rate and fertilization rates, and significantly prolonged durations of infertility. It was noted however, that in regard to clinical pregnancy rates, there was no significant difference between the two groups. Based on the case study results, it was concluded that HBV infection was likely to cause infertility. | The following case study investigated the effects of hepatitis B virus (HBV) infection on sperm parameters, ovarian stimulation, and outcomes of in vitro fertilization (IVF) and embryo transfer, as the impact of HBV on human infertility was questionable. During this study, a total of 224 couples were identified, where either one or both partners were HBsAg-seropositive, and were undergoing their first IVF and embryo transfer cycle. The morphology of their sperm was analysed, as was the quality of their embryo rate, the duration of infertility and their fertilization rates, and then compared to those of 448 HBsAg-seronegative couples. In all four cases, the results of the HBsAg-seropositive couples were inferior to those of the HBsAg-seronegative couples, expressing significantly lower normal sperm morphology, top-quality embryo rate and fertilization rates, and significantly prolonged durations of infertility. It was noted however, that in regard to clinical pregnancy rates, there was no significant difference between the two groups. Based on the case study results, it was concluded that HBV infection was likely to cause infertility. | ||
===Article 2=== | ====Article 2==== | ||
<pubmed>24602756</pubmed> | <pubmed>24602756</pubmed> | ||
The following case study sought to investigate whether assisted reproductive technology (ART) treatments had any impact on the sex ratio of babies born. Using the United Kingdom records of women who have conceived children between 2000 and 2010 using intrauterine insemination, IVF, or intracytoplasmic sperm injection (ICSI), the records of a total of 106,066 babies born to 76,994 mothers were analysed. The results showed that each form of ART resulted in a varied sex ratio, the most significant variation occurring from IVF with 52.1% of babies born male, and the least variation occurring from ICSI embryo transfer, with 49.3% of babies being born male. It was also found that when the embryos were transferred during the blastocyst stage in ICSI and IVF, as opposed to during the early cleavage-stage ET, it resulted in approximately 6% more males being born. It was concluded however, that due to the significantly increasing number of babies born using ART treatments, more research was needed into the causes of the gender bias after such treatments. | The following case study sought to investigate whether assisted reproductive technology (ART) treatments had any impact on the sex ratio of babies born. Using the United Kingdom records of women who have conceived children between 2000 and 2010 using intrauterine insemination, IVF, or intracytoplasmic sperm injection (ICSI), the records of a total of 106,066 babies born to 76,994 mothers were analysed. The results showed that each form of ART resulted in a varied sex ratio, the most significant variation occurring from IVF with 52.1% of babies born male, and the least variation occurring from ICSI embryo transfer, with 49.3% of babies being born male. It was also found that when the embryos were transferred during the blastocyst stage in ICSI and IVF, as opposed to during the early cleavage-stage ET, it resulted in approximately 6% more males being born. It was concluded however, that due to the significantly increasing number of babies born using ART treatments, more research was needed into the causes of the gender bias after such treatments. | ||
Revision as of 11:23, 13 August 2014
Online Assessment
Lab 1 Assessment
Article 1
<pubmed>24760595</pubmed> The following case study investigated the effects of hepatitis B virus (HBV) infection on sperm parameters, ovarian stimulation, and outcomes of in vitro fertilization (IVF) and embryo transfer, as the impact of HBV on human infertility was questionable. During this study, a total of 224 couples were identified, where either one or both partners were HBsAg-seropositive, and were undergoing their first IVF and embryo transfer cycle. The morphology of their sperm was analysed, as was the quality of their embryo rate, the duration of infertility and their fertilization rates, and then compared to those of 448 HBsAg-seronegative couples. In all four cases, the results of the HBsAg-seropositive couples were inferior to those of the HBsAg-seronegative couples, expressing significantly lower normal sperm morphology, top-quality embryo rate and fertilization rates, and significantly prolonged durations of infertility. It was noted however, that in regard to clinical pregnancy rates, there was no significant difference between the two groups. Based on the case study results, it was concluded that HBV infection was likely to cause infertility.
Article 2
<pubmed>24602756</pubmed> The following case study sought to investigate whether assisted reproductive technology (ART) treatments had any impact on the sex ratio of babies born. Using the United Kingdom records of women who have conceived children between 2000 and 2010 using intrauterine insemination, IVF, or intracytoplasmic sperm injection (ICSI), the records of a total of 106,066 babies born to 76,994 mothers were analysed. The results showed that each form of ART resulted in a varied sex ratio, the most significant variation occurring from IVF with 52.1% of babies born male, and the least variation occurring from ICSI embryo transfer, with 49.3% of babies being born male. It was also found that when the embryos were transferred during the blastocyst stage in ICSI and IVF, as opposed to during the early cleavage-stage ET, it resulted in approximately 6% more males being born. It was concluded however, that due to the significantly increasing number of babies born using ART treatments, more research was needed into the causes of the gender bias after such treatments.
Lab Attendance
Lab 1 --Z3465654 (talk) 12:45, 6 August 2014 (EST)
Lab 2 --Z3465654 (talk) 11:18, 13 August 2014 (EST)
